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The evolutionary origin of the genetic code (A10)

Subject Area Biochemistry
Term since 2024
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 521256690
 
The genetic code is a crucial mechanism of life that links a three-letter nucleobase code with the corresponding amino acid, thereby encoding proteins from genetic information. Despite its importance, the evolutionary origin of the genetic code remains poorly understood. We will use a novel sequencing-based high-throughput method to test various theories and proposals about the origin of coded peptide synthesis. Our experiments aim to shed light on whether the genetic code was a random accident or a consequence of molecular reactivities and affinities.
DFG Programme CRC/Transregios
Project Head Professor Dr. Andres Jäschke, since 1/2024
 
 

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