Project Details
Identification of regulatory elements responsible for genomic imprinting in mammals
Applicant
Privatdozentin Dr.-Ing. Martina Paulsen
Subject Area
Human Genetics
Term
from 2002 to 2010
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 5370906
Final Report Year
2010
Final Report Abstract
No abstract available
Publications
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2003. Imprinted microRNA genes transcribed antisense to a reciprocally imprinted retrotransposon-like gene. Nature Genetics 34: 261-262
Seitz, H., N. Youngson, S.P. Lin, S. Dalbert, M. Paulsen, J.P. Bachellerie, A.C. Ferguson-Smith and J. Cavaille
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2003. The potential role of gene duplications in the evolution of imprinting mechanisms. Human Molecular Genetics 12 Spec No 2: R215-220
Walter, J., and M. Paulsen
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(2004) Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation. Nat Genet, 36, 1291-1295
Lewis, A., Mitsuya, K., Umlauf D., Smith, P., Dean, W., Walter, J., Higgins, M., Feil, R. and Reik, W.
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2005. Evolution of the Beckwith-Wiedemann syndrome region in vertebrates. Genome Research 15: 146-153
Paulsen, M., T Khare, C. Burgard, S. Tierling and J. Walter
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2006. Tandem repeats in the CpG islands of imprinted genes. Genomics 88: 323-332
Hutter, B., V. Helms and M. Paulsen
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2006. High-resolution map and imprinting analysis of the Gtl2-Dnchc1 domain on mouse chromosome 12. Genomics 87: 225-235
Tierling, S., S. Dalbert, S. Schoppenhorst, C.E. Tsai, S. Oliger, A.C. Ferguson-Smith, M. Paulsen and J. Walter
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2006. RNA dependent gene silencing and epigenetics in animals. In "Small RNAs", Editors: W. Nellen and C. Hammann. Springer, Heidelberg: 179-200
Paulsen, M., S. Tieriing. S. Barth and J. Walter
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2009. The Begain gene marks the centromeric boundary of the imprinted region on mouse chromosome 12. Mamm Genome, epub ahead of print
Tierling, S., G. Gasparoni, N. Youngson, and M. Paulsen