Project Details
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Identification and characterization of Shinga toxin-independent virulence factors of enterohemorrhagic Escherichia coli which contribute to vascular endothelium injury

Subject Area Parasitology and Biology of Tropical Infectious Disease Pathogens
Term from 2002 to 2010
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 5390014
 
Final Report Year 2010

Final Report Abstract

No abstract available

Publications

  • 2004. Characterization of cytolethal distending toxin genes and expression in Shiga toxin-producing Escherichia coli strains of non-0157 serogroups. Infect. Immun. 72:1812- 1816
    Bielaszewska, M., M. Fell, L. Greune, R. Prager, A. Fruth, H. Tschäpe, M. A. Schmidt, H. Karch
  • 2005. Consequences of enterohaemorrhagic Escherichia coli infection for the vascular endothelium. Thromb. Haemost. 94:312-318
    Bielaszewska, M., H, Karch
  • 2005. Effects of the cytolethal distending toxin from enterohemorrhagic Escherichia coli 0157:H on human endothelial cells. Infect. Immun. 73:552-562
    Bielaszewska, M., B. Sinha, B. Hasslinger, T. Kuczius, H. Karch
  • 2005. Enterohaemorrhagic Escherichia coli in human medicine. Int. J. Med. Microbiol. 295:405-418
    Karch, H., P.I. Tarr, M. Bielaszewska
  • 2006. Cytolethal distending toxin in Escherichia coli 0157:H7: Spectrum of conservation, structure, and endothelial toxicity. J. Clin. Microbiol. 44: 1844-1846
    Friedrich, A. W., S. Lu, M. Bielaszewska, R. Prager, P. Bruns, J.-G. Xu, H. Tschäpe, H. Karch
  • 2006. New aspects in the pathogenesis of enteropathic hemolytic uremic syndrome. Semin. Thromb. Hemost. 32:105-112
    Karch, H., A, W. Friedrich, A. Gerber, L. B. Zimmerhackl, M. A. Schmidt, M. Bielaszewska
  • 2007. Enterohaemorrhagic Escherichia coli 026:H11/H-: a human pathogen in emergence. Berl. Munch. Tierarztl. Wochenschr. 120:279-287
    Bielaszewska, M., W. Zhang, A. Mellmann, H. Karch
  • 2007. Hemolysin from Shiga toxin-negative Escherichia coli 026 strains injures microvascular endothelium. Microbes Infect. 9:282-290
    ldick, T., M. Bielaszewska, W. Zhang, J. Brockmeyer, H. Schmidt, A.W. Friedrich, K.S. Kim, M.A. Schmidt, H. Karch
  • 2008. Glycosphingolipids in vascular endothelial cells: relationship of heterogeneity in Gb3Cer/CD77 receptor expression with differential Shiga toxin 1 cytotoxicity. Glycoconj. J. 25:291-304
    Schweppe, C.H., M. Bielaszewska, G. Pohlentz, A.W. Friedrich, H. Büntemeyer, M.A. Schmidt, K.S. Kim, J. Peter-Katalinic, H. Karch, J. Müthing
  • 2009. Shiga toxin, cytolethal distending toxin, and hemolysin repertoires in clinical Escherichia coli 091 isolates. J. Clin. Microbiol. 47:2061-2066
    Bielaszewska, M., F, Stoewe, A. Fruth, W. Zhang, R. Prager, J. Brockmeyer, A. Mellmann, H. Karch, A.W. Friedrich
  • 2009. Shiga toxins, glycosphmgolipid diversity, and endothelial cell injury. Thromb. Haemost. 101:252-264
    Müthing, J., CH. Schweppe, H. Karch, A.W. Friedrich
  • 2009. Vacuolisation of human microvascular endothelial cells by enterohaemorrhagic Escherichia coli. Thromb. Haemost. 102:1080-1092
    Bielaszewska, M., A. Bauwens, L. Greune, B. Kemper, U. Dobrindt, J.M. Geelen, K.S. Kim, M.A. Schmidt, H, Karch
  • 2009. Vesicular stabilization and activity augmentation of enterohaemorrhagic Escherichia coli haemolysin. Mol. Microbiol. 71:1496-1508
    Aldick, T., M. Bielaszewska, B.E. Uhlin, H.-U. Humpf, S.N. Wai, H. Karch
 
 

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