Project Details
Projekt
Analysis of prophyrin-mediated signaling pathways for the control of nuclear genes by the chloroplast
Applicant
Professor Dr. Christoph Friedrich Beck
Subject Area
Plant Biochemistry and Biophysics
Term
from 2003 to 2009
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 5470163
The project is focussed on one aspect of intracellular communication: the signaling from chloroplast to nucleus. Studies with higher plants and our work with Chlamydomonas have provided evidence for a role of tetrapyrroles and of enzymes involved in their biosynthesis in chloroplast-to-nucleus signaling. The goal of the project is the molecular and functional characterization of genes and molecules that mediate this communication. For this purpose, we will identify mutants defective in this communication and characterize the altered genes and their products. In a complementing approach, an enhancer sequence that responds to a chloroplast signal will be employed to characterize protein(s) that bind to it. And in mutants that exhibit a deregulation in both, their chlorophyll precursor levels and in the expression of nuclear genes involved in tetrapyrrole biosynthesis, we plan to dissect the basis for the altered signaling from chloroplast to nucleus.
DFG Programme
Research Units
