Analyse der molekulargenetischen und biochemischen Heterogenität im Skelettmuskel von Patienten mit mitochondrialen Zytopathien

• Applicant: Professor Dr. Wolfram S. Kunz, since 1/2006
• Subject Area: Molecular Biology and Physiology of Neurons and Glial Cells
• Term: from 2003 to 2008
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5412408

• Final Report Year: 2008

Final Report Abstract

No abstract available

Publications

• Diagnostic value of mitochondrial DNA mutation analysis in juvenile unilateral ptosis. Graefes Arch Clin Exp Ophthalmol. 2005;243(4):380-2
  Okulla T, Kunz WS, Klockgether T, Schröder R, Kornblum C
  
• Recombination of mitochondrial DNA in skeletal muscle of individuals with multiple mitochondrial DNA heteroplasmy. Nat Genet. 2005;37(8):873-7
  Zsurka G, Kraytsberg Y, Kudina T, Kornblum C, Elger CE, Khrapko K, Kunz WS
  
• Inheritance of mitochondrial DNA recombinants in double-heteroplasmic families: potential implications for phylogenetic analysis. Am J Hum Genet. 2007;80(2):298-305
  Zsurka G, Hampel KG, Kudina T, Kornblum C, Kraytsberg Y, Elger CE, Khrapko K, Kunz WS