Die adaptive Immunantwort bei Sepsis und Multiorganversagen: pathophysiologischer Stellenwert des IKK/NF-kappa B-Signalweges

• Applicant: Professor Dr. Uwe Senftleben
• Subject Area: Anaesthesiology
• Term: from 2003 to 2007
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5412581

• Final Report Year: 2008

Final Report Abstract

No abstract available

Publications

• Escherichia coli prevents phagocytosis-induced death of macrophages via classical NF-kappaB signaling, a link to T-cell activation. Infect Immun. 2006 Oct;74(10):5989-6000
  Groesdonk HV, Schlottmann S, Richter F, Georgieff M, Senftleben U
  
• Enhancement of NF-kappaB activation in lymphocytes prevents T cell apoptosis and improves survival in murine sepsis. J Immunol. 2007 Dec 15;179(12):8083-9
  Groesdonk HV, Wagner F, Hoffarth B, Georgieff M, Senftleben U