Clinical Coordination Unit
Final Report Abstract
This central service project performed two tasks: 1. Integration of local databases and setup of a central database embedded in the Hospital Information System (HIS) medico//s 2. Statistical support for the project partners. In the past, relevant data of donors and recipients were stored in local databases. These databases are replaced by a central database which is embedded in the Hospital Information System (HIS) medico//s. Project S-I coordinated the design and set-up of this central database which required the specification of an item catalogue which satisfies all user requirements of our project partners. Next, Project S-I embedded the catalogue in the HIS medico//s system. The central database contains more than 200 harmonized items which cover important aspects of living-related and/or cadaveric liver transplantations (e.g. details of transplantation surgery of recipient and donor, blood transfusions, lab data, immunosuppression, complications related to transplantation, follow-up information of recipient). Project S-I also provided statistical support at various levels (sometimes beyond the focus of liver transplantation). Starting with basic statistical advice for the planning and conduct of experiments - including sample size considerations - to advice regarding the use of statistical analysis software packages. Moreover, Project S-I also performed non-standard statistical analyses where required and contributed to publications (i.e. performed analyses, created figures and tables and wrote parts of the manuscripts). Using the infrastructure of the Center for Clinical Trials Essen we also supported our clinical partners (Prof. Minor, Prof. Paul) in a successful DFG proposal of a clinical trial.
Publications
- Evaluation of organ donor card holders among public officials of a major German city. Transplant Proc 2009, 41: 2505-2508
Heuer M, Hertel S, Wirges U, Philipp T, Gerken G, Paul A, Kaiser GM
(See online at https://doi.org/10.1016/j.transproceed.2009.06.127) - Attitude of health care professionals to organ donation: two surveys among the staff of a German university hospital. Transplant Proc 2010, 42: 126-129
Radunz S, Hertel S, Schmid KW, Heuer M, Stommel P, Frühauf NR, Saner FH, Paul A, Kaiser GM
(See online at https://doi.org/10.1016/j.transproceed.2009.12.034) - Radioembolization with yttrium-90 glass microspheres in hepatocellular carcinoma: European experience on safety and long-term survival. Hepatology 2010, 52: 1741-1749
Hilgard P, Hamami M, Fouly AE, Scherag A, Müller S, Ertle J, Heusner T, Cicinnati VR, Paul A, Bockisch A, Gerken G, Antoch G
(See online at https://doi.org/10.1002/hep.23944) - Tumor markers as a diagnostic key for hilar cholangiocarcinoma. Eur J Med Res 2010, 15: 357-361
Juntermanns B, Radunz S, Heuer M, Hertel S, Reis H, Neuhaus JP, Vernadakis S, Trarbach T, Paul A, Kaiser GM
(See online at https://doi.org/10.1186/2047-783X-15-8-357) - Assessment of a chloride-poor vs. a chloride-containing modified HTK solution in a rat liver transplantation model. Liver Transpl 2011, 17: 650-660
Fingas CD, Wu S, Gu Y, Wohlschlaeger J, Scherag A, Dahmen U, Paul A, de Groot H, Rauen U
(See online at https://doi.org/10.1002/lt.22275) - Impact of immunosuppressive therapy on hepatitis C infection after renal transplantation. Clin Nephrol 2011, 75: 16-25
Kahraman A, Witzke O, Scherag A, Pütter C, Miller M, Dechêne A, Ross SR, Gerken G, Hilgard P
(See online at https://doi.org/10.2379/CNP75016)
