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SFB 413:  Dynamics and regulation of cytoskeleton dependent motile activities

Subject Area Biology
Term from 1998 to 2007
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 5481992
 
Collaborative research centre 413 studies the molecular principles of the dynamics in the cytoskeleton; the projects can be grouped into three major areas:(A) Molecular motors and cytoskeleton-associated proteins: The studies focus on biochemical and functional characterization of cytoskeletal proteins, they include cell biological and genetic approaches, and the major filamentous systems under investigation are microtubules and actin filaments, including the associated proteins.(B) Supramolecular und cellular movements: In difference to studies on single molecules, the projects in this area are dealing with complex motile events like phagocytosis, whole cell motility, movement of organelles, cellular responses during and after infection with pathogens.(C) Structure of cytoskeletal proteins and biophysical approaches: The rather biologically and medically oriented research is complemented by groups with interests in biophysical and structural research. The biophysical projects help for example to understand viscoelastic properties of the cytoskeleton and the cytoplasm, crystallography and NMR will provide the basis for our understanding of structure/function relationships of the cytoskeleton at the molecular level.
DFG Programme Collaborative Research Centres

Completed projects

Participating University Technische Universität München (TUM)
Participating Institution Max-Planck-Institut für Biochemie (MPIB)
 
 

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