600 MHz NMR-Spectrometer with Probehead

• Subject Area: Analytical Chemistry
• Term: Funded in 2024
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 551922835

In order to modernize an existing 600 MHz NMR spectrometer, the Chemistry Department of the RPTU Kaiserslautern-Landau is applying for a new console, including a new variable temperature control unit that is compatible with the 14T magnet and sample changer previously used as well as with the four existing probe-heads. In addition, to extend the number previous measurement options, a broadband-optimized triple resonance probe-head for the observation of nuclei in the broadband range from 31P to 109Ag with 1H and/or 19F decoupling as well as with 1H and/or 19F observation(s) is being applied for. The existing NMR device is the most powerful NMR spectrometer in the department in terms of sensitivity and resolution. Using this device, NMR spectroscopic characterizations of compounds are carried out on 1H, 10/11B, 13C, 2D, 17O, 19F, 15N, 31P, 29Si, 51V, 109Ag, and 195Pt nuclei. When one- and two-dimensional spectra are obtained, not only can the structures of compounds be elucidated and the reactivity of dissolved substances investigated, but molecular properties such as magnetic properties of dissolved paramagnetic complexes can also be determined. The time and temperature dependence of one- and two-dimensional spectra provide thermodynamic and kinetic parameters for characterizing reactions and can lead to a better understanding of reaction mechanisms. These application examples show that NMR spectroscopy is generally one of the most important analysis methods in our field and that the high-resolution 600 MHz NMR spectrometer is particularly essential to the modern NMR equipment at this research site. Our device is now over 20 years old and, therefore, often requires repair. In particular, there is a need for immediate action as spare parts are becoming increasingly difficult to obtain because the manufacturer has stopped producing spare parts for the old console. Some software updates are also no longer possible due to outdated hardware. Modernizing the console will not only preserve the functionality of the device for the near future, but also bring the device up to date with the latest developments, thus ensuring better performance. The new probe-head would also enable the department to examine hetero-nuclei under 1H and/or 19F decoupling mode(s) or the hetero-nucleus together with the 1H and/or 19F nuclei in fluorine-containing compounds. The procurement of the new console and probe-head would help ensure that the 600 MHz NMR device will continue to be available for research projects. This, in turn, would guarantee the department’s ability to carry out third-party funded projects. Additionally, high-quality, contemporary NMR equipment would maintain and even strengthen the competitiveness of Kaiserslautern as research location.

• DFG Programme: Major Research Instrumentation
• Major Instrumentation: 600 MHz-NMR-Konsole mit Probenkopf
• Instrumentation Group: 1740 Hochauflösende NMR-Spektrometer
• Applicant Institution: Rheinland-Pfälzische Technische Universität Kaiserslautern-Landau
• Leader: Professor Hans-Jörg Krüger, Ph.D.