FOR 5953:  Intervening in the Innate Immune Response early after Myocardial Infarction

• Subject Area: Medicine
• Term: since 2026
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 555094884

No abstract available

• DFG Programme: Research Units

Projects

• Biosample management, data management, and integrative data science (Applicants Altmann, Heidi ;  Linke, Axel ;  Pauling, Ph.D., Josch )
• Cell-based therapeutic strategies to invigorate resident cardiac macrophages (Applicants Kopaliani, Irakli ;  Sieweke, Michael )
• Coordination Funds (Applicant El-Armouche, Ali )
• Experimental models of myocardial infarction, phenotyping and immune-metabolic characterisation of patients with acute MI (Applicants El-Armouche, Ali ;  Guan, Kaomei ;  Mirtschink, Peter )
• Impact of sympathetic activation and exercise training on innate immune cell phenotypes after myocardial infarction (Applicants Kämmerer, Susanne ;  Linke, Axel )
• Macrophage ferroptosis in myocardial infarction (Applicants Fedorova, Ph.D., Maria ;  Linkermann, Andreas ;  Tonnus, Wulf )
• Metabolic reprograming of sexually dimorphic macrophage responses after myocardial infarction (Applicants Alexaki, Vasileia Ismini ;  Schubert, Mario )
• Microfluidic organ-on-a-chip system: Unravelling the function and therapeutic potential of macrophages in ischemia-reperfusion injury (Applicant Guan, Kaomei )
• Myeloid HIF Signaling as a Therapeutic Target in Post-Infarct Inflammation and Repair (Applicants Mirtschink, Peter ;  Wielockx, Ph.D., Ben )
• Targeting the CX3CL1/CX3CR1 axis to attenuate neutrophil infiltration early after myocardial infarction (Applicants El-Armouche, Ali ;  Klapproth, Erik )
• The role of clonal hematopoiesis driven by DNMT3A mutations in regulating innate immune cell functions in the context of myocardial infarction (Applicants Chavakis, Triantafyllos ;  Kalafati, Lydia )

• Spokesperson: Professor Dr. Ali El-Armouche