Die Rolle des Trypsins als Schlüsselenzym der proteolytischen Aktivierungskaskade bei akuter Pankreatitis

• Applicant: Professor Dr. Walter Halangk (†)
• Subject Area: General and Visceral Surgery
• Term: from 2007 to 2009
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 55969609

• Final Report Year: 2010

Final Report Abstract

No abstract available

Publications

• Caerulein hyperstimulation results in an inhibitorinsensitive trypsin activity in the mouse pancreas. EPC-Meeting 2007, New Castle, U.K. (als Abstract publiziert in Pancreatology 7, p. 263
  Wartmann T, Gilbert N, Butueva M, Brandt-Nedelev B, Lippert H, Mayerle J, Lerch MM, Halangk W
  
• Charakterisierung der inhibitor-insensitiven Trypsinaktivität bei experimenteller Pankreatitis der Maus. DPG-Meeting 2007, Dresden
  Butueva M, Brandt-Nedelev B, Sahin-Toth M, Lerch MM, Haiangk, Wartmann T
  
• Experimental pancreatitis results in an inhibitor-insensitive trypsin activity in the mouse pancreas. International Meeting on Proteinases 2007, Portoroz, Slowenien
  Halangk W, Wartmann T, Gilbert N, Butueva M. Brandt-Nedelev B, Lippert H, Lerch MM
  
• Proteomanalyse, Identifizierung und Charakterisierung rekombinanter Trypsinogen-Isoformen der Maus. DPC-Meeting 2007, Dresden
  Wartmann T, Butueva M, Brandt-Nedelev B, Makarov P, Lerch MM, Halangk W
  
• Trypsin activity in the mouse pancreas after supramaximal caerulein stimulation represents an inhibiotr-insensitive isoform. Digestive Disease Week 2008, San Diego (als Abstract publiziert in Gastroenterology 143 (4), A127)
  Halangk W, Butueva M, Lerch MM, Sahin-Toth M, Wartmann T
  
• Trypsin(ogen) 4 represents an inhibotr-insensitive isoform in the Mouse pancreas ans is activiated during experimental pancreatitis. Meeting der APA 2009, Honolulu, USA (als Abstract publiziert in Pancreas 2009, 38, p. 1000)
  Halangk W, Butueva M, Lerch MM, Sahin-Toth M, Wartmann T