Common resources of the research unit

• Antragsteller: Professor Dr. Andreas Zimmer
• Fachliche Zuordnung: Biologische Psychiatrie
• Förderung: Förderung von 2008 bis 2016
• Projektkennung: Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 42860621

• Erstellungsjahr: 2017

Zusammenfassung der Projektergebnisse

The main task of CP2 was the establishment of animal colonies providing genetic mouse models for all investigators in the Research Unit. CP 2 also provided administrative support and facilitated scientific exchange within the Research Unit by organizing regular meetings and workshops.

Projektbezogene Publikationen (Auswahl)

• (2013). Loss of CB1 receptors leads to differential age-related changes in reward-driven learning and memory. Front Aging Neurosci. Epub 2012 Dec 5
  Albayram, Onder; Bilkei-Gorzo, Andras & Zimmer, Andreas
  
• (2013). Inhibition of endocannabinoid-degrading enzyme fatty acid amide hydrolase increases atherosclerotic plaque vulnerability in mice. J Mol Cell Cardiol, 66:126-132
  Hoyer, Friedrich Felix; Khoury, Mona; Slomka, Heike; Kebschull, Moritz; Lerner, Raissa; Lutz, Beat; Schott, Hans; Lütjohann, Dieter; Wojtalla, Alexandra; Becker, Astrid; Zimmer, Andreas & Nickenig, Georg
  
• (2014). The CB1 Receptor as an Important Mediator of Hedonic Reward Processing. Neuropsychopharmacology, 39(10):2387-96
  Friemel, Chris M; Zimmer, Andreas & Schneider, Miriam
  
• (2014). The endocannabinoid-CB2 receptor axis protects the ischemic heart at the early stage of cardiomyopathy. Basic Res Cardiol, 109(4):425
  Duerr, Georg D.; Heinemann, Jan C.; Suchan, Georg; Kolobara, Elvis; Wenzel, Daniela; Geisen, Caroline; Matthey, Michaela; Passe-Tietjen, Kristine; Mahmud, Walid; Ghanem, Alexander; Tiemann, Klaus; Alferink, Judith; Burgdorf, Sven; Buchalla, Rainer; Zimmer, Andreas; Lutz, Beat; Welz, Armin; Fleischmann, Bernd K. & Dewald, Oliver
  
• (2014). Cannabinoid receptor 2 deficiency results in reduced neuroinflammation in an Alzheimer's disease mouse model. Neurobiol Aging, 36:710-719
  Schmöle, Anne-Caroline; Lundt, Ramona; Ternes, Svenja; Albayram, Önder; Ulas, Thomas; Schultze, Joachim L.; Bano, Daniele; Nicotera, Pierluigi; Alferink, Judith & Zimmer, Andreas
  
• (2014). CB2 receptor-mediated effects of pro-inflammatory macrophages influence survival of cardiomyocytes. Life Sci, 138 (2015) 18-28
  Heinemann, Jan C.; Duerr, Georg D.; Keppel, Katharina; Breitbach, Martin; Fleischmann, Bernd K.; Zimmer, Andreas; Wehner, Sven; Welz, Armin & Dewald, Oliver
  
• (2015). Activation of Endocannabinoid System Is Associated with Persistent Inflammation in Human Aortic Aneurysm. Biomed Res Int, 2015:456582
  Gestrich, Christopher; Duerr, Georg D.; Heinemann, Jan C.; Meertz, Anne; Probst, Chris; Roell, Wilhelm; Schiller, Wolfgang; Zimmer, Andreas; Bindila, Laura; Lutz, Beat; Welz, Armin & Dewald, Oliver
  
• (2015). Enhanced microglial activity in FAAH-/- animals. Life Sci, 138:52-56
  Ativie, F.; Albayram, O.; Bach, K.; Pradier, B.; Zimmer, A. & Bilkei-Gorzo, A.
  
• (2015). Inhibition of FAAH reduces nitroglycerin-induced migraine-like pain and trigeminal neuronal hyperactivity in mice. Eur Neuropsychopharmacol, 25(8):1388-96
  Nozaki, Chihiro; Markert, Astrid & Zimmer, Andreas
  
• (2016). Lack of hippocampal CB1 receptor desensitization by Δ(9)-tetrahydrocannabinol in aged mice and by low doses of JZL 184. Naunyn Schmiedebergs Arch Pharmacol. 389(6):603-12
  Feliszek, Monika; Bindila, Laura; Lutz, Beat; Zimmer, Andreas; Bilkei-Gorzo, Andras & Schlicker, Eberhard