Binding forces in quasi one- and two- dimensional geometries (C03)

• Subject Area: Experimental Condensed Matter Physics ; Experimental and Theoretical Physics of Polymers
• Term: from 2008 to 2019
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 32049920

This project aims at a quantitative description of the influence of multivalency on the intreractions in biologically relevant model systems in quasi one- and two-dimensional geometries. Single-Molecule Force Spectroscopy shall be used to quantify the binding of single multivalent glycoproteins with its ligands. Scanning Force Microscopy shall be used to investigate multimerisations to supramolecular copolymers. Finally, the multivalency of graphene layers functionalized with polyglycerols shall be used to conformly coat viruses and bacteria in order to block the biological response of these pathogens.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 765: Multivalency as Chemical Organisation and Action Principle: New Architectures, Functions and Applications
• Applicant Institution: Freie Universität Berlin
• Co-Applicant Institution: Humboldt-Universität zu Berlin
• Project Head: Professor Dr. Jürgen P. Rabe