Go directly to content Go directly to font size and contrast

Project Details

Institution

Print View

Goethe-Universität Frankfurt am Main
Fachbereich Biochemie, Chemie und Pharmazie
Institut für Organische Chemie und Chemische Biologie

Address Max-von-Laue-Straße 7
60438 Frankfurt am Main
Deutschland

GERiT This institution in GERiT

60438 Frankfurt am Main

Projects

Research Grants
- Current projects
  - Improvement of the NMR structural quality for RNA and DNA
    (Applicant Schwalbe, Harald )
  - in-cell NMR of DNA G4 - structure and folding
    (Applicant Schwalbe, Harald )
  - Light-activatable cytostatic compounds
    (Applicant Heckel, Alexander )
  - SARS-CoV-2-RNA: Understanding the RNA architecture of SARS-CoV-2
    (Applicants Schwalbe, Harald ; Weigand, Julia Erika ; Wöhnert, Jens )
- Completed projects
Independent Junior Research Groups
- Completed projects
  - Cations in charge of RNA folding and function: Realistic modeling and robust predictions
    (Applicant Schwierz, Ph.D., Nadine )
  - Ortsaufgelöste Genregulation mit photoaktivierbarer RNA
    (Applicant Heckel, Alexander )
Priority Programmes
- Current projects
  - NMR and biophysical characterization of structure and dynamics of µ-proteins and their complexes.
    (Applicant Schwalbe, Harald )
- Completed projects
Research Units
- Current projects
  - Effects of glycosylation on protein structure, function and dynamics
    (Applicant Schwalbe, Harald )
  - FOR 2509: The concert of dolichol-based glycosylation: from molecules to disease models
    (Spokesperson Strahl, Sabine )
- Completed projects
  - Effects of glycosylation on protein structure, function and dynamics
    (Applicant Schwalbe, Harald )
New Instrumentation for Research
- Current projects
  - Nanoseond Ultra-Rapid Freeze Quenching for Time-resolved Structural Biology
    (Applicant Schwalbe, Harald )
Collaborative Research Centres
- Current projects
  - Modulation of tyrosine receptor signaling investigated by NMR spectroscopy
    (Project Head Schwalbe, Harald )
- Completed projects
  - Analyse von RNA
    (Project Heads Engels, Joachim W. ; Göbel, Michael )
  - Central Tasks of the Collaborative Research Centre
    (Project Head Schwalbe, Harald )
  - Chemically modified RNA for Analytics and Therapy
    (Project Heads Engels, Joachim W. ; Heckel, Alexander )
  - Conformational dynamics of RNA regulation elements studied by NMR spectroscopy
    (Project Head Schwalbe, Harald )
  - DNA-bindende Polyamide als neues sequenzspezifisches Strukturelement für DNA-Nanoarchitekturen
    (Project Head Heckel, Alexander )
  - High Resolution Spectroscopy Investigations of T-Cell Activation and G Protein Coupled Receptors
    (Project Head Schwalbe, Harald )
  - Light-responsive riboswitches and miRNA activity
    (Project Head Heckel, Alexander )
  - New tools to study the dynamics of RNA and RNP distribution in neuronal cells
    (Project Heads Heckel, Alexander ; Schuman, Erin M. )
  - NMR Investigations of Mammalian Rhodopsin and of Membrane-associated Protein GARP2
    (Project Head Schwalbe, Harald )
  - NMR investigations of retinal binding proteins
    (Project Head Schwalbe, Harald )
  - NMR-spectroscopic investigations of RNA and RNA-Ligand-Complexes
    (Project Head Schwalbe, Harald )
  - Organic Synthesis of photolabile cofactors and NMR investigation of antibody fragments reporting Rieske domain movements of the bc1 complex
    (Project Head Schwalbe, Harald )
  - SFB 579: RNA-Ligand Interactions
    (Spokesperson Schwalbe, Harald )
  - SFB 902: Molecular Principles of RNA-based Regulation
    (Spokesperson Schwalbe, Harald )
  - Structural Biology of SARS-CoV-2 by NMR spectroscopy (Covid19-NMR)
    (Project Head Schwalbe, Harald )
  - Synthesis of rigid spin labels and of other chemical tools to investigate RNA structure
    (Project Head Göbel, Michael )
  - Synthetic small molecules interfering with RNA functions
    (Project Head Göbel, Michael )
  - Zentrale Verwaltung des SFB
    (Project Heads Göbel, Michael ; Schwalbe, Harald )
Major Research Instrumentation
- Completed projects
Research Fellowships
- Completed projects
  - Enantioselective Iron- or Cobalt-Catalyzed Hydrohydroxyalkylation of Butadiene
    (Applicant Tauber, Johannes )
  - Structure and function of factors mediating Tetrahymena telomerase action at telomeres
    (Applicant Helmling, Christina )
WBP Fellowship
- Current projects
  - Metabolic characterisation of glioblastoma and ovarian tumours and identification of metabolic biomarkers of drug resistance using metabolic imaging
    (Applicant Alshamleh, Islam )
Major Instrumentation Initiatives
- Completed projects
  - Development of Biomolecular High Field Pulsed DNP and cwDNP MAS-NMR Applications
    (Applicant Glaubitz, Clemens )
CRC/Transregios
- Current projects
  - Vascular gene expression control through DNA:DNA:RNA triplex-formation by lncRNAs
    (Project Heads Brandes, Ralf P. ; Schwalbe, Harald )
Research Training Groups
- Completed projects
  - GRK 1986: Complex Scenarios of Light-Control
    (Spokesperson Heckel, Alexander )
Clusters of Excellence
- Completed projects
  - EXC 115: Macromolecular Complexes
    (Spokespersons Dötsch, Volker ; Schwalbe, Harald )

© 2024 DFG Disclaimer / Copyright / Privacy Policy