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Institution
Universitätsklinikum Ulm
Klinik für Kinder- und Jugendmedizin
Address
Eythstraße 24
89075 Ulm
Deutschland
GERiT
This institution in GERiT
89075 Ulm
Projects
Research Grants
Current projects
Efficacy of MV-NIS oncolytic measles virus against relapsed / refractory pediatric ALL and safety in the young and markedly immunocompromised primate
(Applicant
Beltinger, Christian
)
How much or little linear ubiquitination makes our metabolism sick? - The role of linear ubiquitination in inflammatory processes in (dys)functional adipose tissue
(Applicant
Zinngrebe, Julia
)
Regulation of T-cell Function Through Changes in Local Membrane Architecture
(Applicant
Lyszkiewicz, Ph.D., Marcin
)
The role of Vascular Endothelial Growth Factor in CNS manifestation of pediatric acute lymphoblastic leukemia
(Applicant
Münch, Vera
)
The role of V(D)J recombination and CD45 isotype expression in human natural killer cell development
(Applicant
Felgentreff, Kerstin
)
Completed projects
Charakterisierung defekter Apoptosesignaltransduktion lymphoblastischer Leukämien in vivo
(Applicant
Stahnke, Karsten
)
Das CD95 (Fas/APO-1)-assoziierte Protein FIST und dessen Signalübertragungsmechanismus
(Applicant
Hug, Hubert
)
Einfluß von Spontanatmung unter partieller Flüssigkeitsbeatmung (PLV) auf die Hämodynamik am Versuchstier mit und ohne Lungenerkrankung
(Applicant
Hummler, Helmut
)
Expression und biologische Wirkung von Insulin-ähnlichen Wachstumsfaktoren (IGFs) und deren Bindungsproteinen während der Differenzierung humaner Adipozyten
(Applicant
Wabitsch, Martin
)
Hirntumortherapie mit TRAIL-exprimierenden Partikeln aus neuralen Progenitoren von humanem Knochenmark und von embryonalen Stammzellen
(Applicant
Beltinger, Christian
)
Identification and enrichment of beige/brown adipocyte progenitors from white adipose tissue for the generation of functional brown fat in humans
(Applicant
Fischer-Posovszky, Pamela
)
Influence of postnatal estradiol and progesterone replacement on the development of bronchopulmony dyplisia in extremely low birth weight infants
(Applicant
Trotter, Andreas
)
Mutationen mitochondrialer und nukleärer apoptoseassoziierter Gene als Ursache der Chemoresistenz akuter lymphatischer Leukämien im Kindesalter
(Applicant
Beltinger, Christian
)
Prospektive Längsschnittstudie zum Einfluß der mütterlichen Bindungshaltung auf die Entwicklung von sehr kleinen Frühgeborenen
(Applicant
Brisch, Karl-Heinz
)
Pulmonary administration of antibiotics during partial liquid ventilation for severe gram-negative pneumonia
(Applicant
Franz, Axel
)
Regulation der Apoptose in humanen Präadipozyten und Adiopzyten
(Applicant
Wabitsch, Martin
)
Regulation of B cell development and function by microRNA-191
(Applicant
Lyszkiewicz, Ph.D., Marcin
)
Regulation of human plasmacytoid dendritic cells by inhibitors of interferon-alpha
(Applicant
Fabricius, Dorit
)
Sensibilisierung Therapie-resistenter Tumorzellen gegenüber Radio- und Chemotherapie-induzierter Apoptose sowie direkte Induktion von Apoptose in Tumorzellen durch den Transfer Apoptose-regulierender Gene
(Applicant
Herr, Ingrid
)
Steuerung von Apoptose in hämatopoetischen Stamm- und Progenitorzellen durch molekulare Modifikation von Apoptosesignalwegen als Grundlage therapeutischer Interventionen
(Applicant
Stahnke, Karsten
)
The role of RAG-induced DNA damage response in iPSC-derived NK cell development
(Applicant
Felgentreff, Kerstin
)
The role of transcription factors in human brown adipose tissue development
(Applicant
Tews, Daniel
)
TRAIL-Rezeptor Kostimulation als Modulator der T-Zellaktivierung und als therapeutischer Ansatz bei der Behandlung der GVHD
(Applicant
Strauß, Gudrun
)
Volumenkontrollierte Beatmung zur Behandlung häufiger und ausgeprägter Hypoxämien bei langzeitbeatmeten Frühgeborenen
(Applicant
Hummler, Helmut
)
Clinical Research Units
Completed projects
Charakterisierung der Apoptosesensitivität leukämieinitiierender Zellen in pädiatrischer aktuer lymphoblastischer Leukämie
(Applicant
Debatin, Klaus-Michael
)
KFO 167: Regulation of Apoptosis and its Deregulation in Disease
(Spokesperson
Debatin, Klaus-Michael
)
Untersuchungen der Resistenzmechanismen nach verschiedenen Bestrahlungsmodalitäten in Tumorzellen und Möglichkeiten der Sensitivierung
(Applicant
Friesen, Ph.D., Claudia
)
Zentralprojekt
(Applicant
Debatin, Klaus-Michael
)
Heisenberg Fellowships
Completed projects
Healthy Fat for a Healthy Life - Targeting Adipocyte Adipose Tissue Function to Maintain and Improve Systemic Metabolism
(Applicant
Fischer-Posovszky, Pamela
)
Heisenberg Professorships
Completed projects
Healthy Fat for a Healthy Life - Targeting Adipocyte Adipose Tissue Function to Maintain and Improve Systemic Metabolism
(Applicant
Fischer-Posovszky, Pamela
)
Heisenberg Grants
Current projects
Healthy Fat for a Healthy Life - Targeting Adipocyte Adipose Tissue Function to Maintain and Improve Systemic Metabolism
(Applicant
Fischer-Posovszky, Pamela
)
Collaborative Research Centres
Current projects
Role of myeloid-derived suppressor cells (MDSCs) in post-traumatic and post-septic immune regulation (Strauß
(Project Head
Strauß, Gudrun
)
The role of white adipose tissue in post-traumatic inflammation and organ dysfunction
(Project Heads
Fischer-Posovszky, Pamela
;
Halbgebauer, Rebecca
)
Completed projects
Attenuated oncolytic measles virus against ALL of childhood: preclinical proof-of-principle and molecular mechanisms
(Project Head
Beltinger, Christian
)
Charakterisierung der durch RBP-Jk vermittelten Repression und Rolle von RBP-Jk in der Lympho-Hämatopoese
(Project Heads
Liptay, Claudia-Susanne
;
Schmid, Roland M.
)
Multi-targeting and identification of synergistic activities to overcome therapy resistance in ALL
(Project Heads
Debatin, Klaus-Michael
;
Meyer, Lüder Hinrich
)
Role of severe obesity on healing of muscle injuries
(Project Heads
Knippschild, Uwe
;
Wabitsch, Martin
)
Streßinduzierte Aktivierung von Apoptosesignalwegen bei der myokardialen Ischämie
(Project Head
Debatin, Klaus-Michael
)
Untersuchung zur Expreson und transkriptionellen Regulation von GADD45, einem potentiellen Zielgen von NF-kB in humanen Pankreaskarziomen
(Project Head
Liptay, Claudia-Susanne
)
Research Fellowships
Completed projects
Interaction of GFAP and the role of Rho:Rho-kinase signalling pathway in astrocytome invasion
(Applicant
Peraud, Aurelia
)
Reconstitution of T-lineage differentiation potential of induced pluripotent stem cells derived from severe combined immunodeficiency patients by retroviral gene transfer.
(Applicant
Felgentreff, Kerstin
)
Major Research Instrumentation
Completed projects
Einzelzell-Massenzytometer
Research Training Groups
Completed projects
GRK 1041: Molecular Diabetology and Endocrinology in Clinical Medicine
(Spokesperson
Böhm, Bernhard Otto
)
GRK 2254: Heterogeneity and evolution in solid tumors (HEIST): Molecular characterization and therapeutic consequences
(Spokesperson
Seufferlein, Thomas
)
Graduate Schools
Completed projects
GSC 270: International Graduate School in Molecular Medicine Ulm
(Spokesperson
Kühl, Michael
)
Additional Information
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