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Project Details

Institution

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Universitätsklinikum Bonn (AöR)
Medizinische Fakultät
Institut für Angeborene Immunität

Address Venusberg-Campus 1
53127 Bonn
Deutschland

GERiT This institution in GERiT

53127 Bonn

Projects

Independent Junior Research Groups
- Completed projects
  - Elucidating inflammasome activation with alpaca single domain antibodies
    (Applicant Schmidt, Florian Ingo )
Priority Programmes
- Completed projects
Research Grants
- Current projects
  - Inflammatory pathways in subtypes of intestinal cancer
    (Applicants Meissner, Felix ; Saur, Dieter )
- Completed projects
  - Indolamin-2,3-Dioxigenase (IDO) induction in T cells as new mechanism of tumor-induced immunosuppression in pancreatic carcinoma
    (Applicants Düwell, Peter ; Schnurr, Maximilian )
Collaborative Research Centres
- Current projects
  - Molecular pathways of gasdermin pore formation and repair
    (Project Heads Latz, Eicke ; Schmidt, Florian Ingo )
  - Multi-omics – Technology and strategic support
    (Project Heads Hiller, Karsten ; Meissner, Felix ; Thiele, Christoph )
  - Preventive interventions in unhealthy nutritional behaviours
    (Project Heads Albrecht, Clemens ; Christ, Anette ; von Stetten, Moritz )
  - Proteomic dissection of cell death-mediated protein release and proteolysis
    (Project Heads Huesgen, Pitter ; Meissner, Felix )
  - Proteomics identification of macrophage-derived signals impacting metaflammation in tissues
    (Project Head Meissner, Felix )
  - Unbiased analysis of Western diet-induced inflammatory responses in metabolic diseases
    (Project Heads Düwell, Peter ; Latz, Eicke )
- Completed projects
  - Dissecting the communication between immune and tumor cells with quantitative proteomics
    (Project Head Meissner, Felix )
  - Functional proteomics dissection of chemotactic protein diversity
    (Project Head Meissner, Felix )
  - Inflammatory pathways in subtypes of intestinal cancer
    (Project Heads Meissner, Felix ; Saur, Dieter )
  - Mechanisms of microbiota-mediated alteration in atherogenesis
    (Project Heads Düwell, Peter ; Latz, Eicke ; Schnurr, Maximilian )
CRC/Transregios
- Current projects
  - Biomarkers and mechanisms of disease progression and outcome in aortic stenosis in humans
    (Project Heads Franklin, Bernardo ; Luetkens, Julian Alexander ; Mauri, Victor ; Shamekhi, Jasmin ; Veulemans, Ph.D., Verena )
  - Functional Proteomics/Metabolomics/Lipidomics and Human Adipocyte Unit
    (Project Heads Dyar, Ph.D., Kenneth A. ; Meissner, Felix ; Pfeifer, Alexander )
  - Systematic dissection of cytosolic DNA sensing and signalling with nanobodies and proteomics
    (Project Heads Hartmann, Gunther ; Meissner, Felix ; Schmidt, Florian Ingo )
  - The CD40/CD40L-axis in aortic aneurysm: defining immune cell interactions and therapeutic targets
    (Project Heads Gerdes, Norbert ; Lutgens, Esther ; Schmidt, Susanne )
  - Transcriptomics and epigenetic data analysis
    (Project Heads Billmann, Maximilian ; Schmidt, Susanne )
- Completed projects
  - Functional proteomics dissection of phagocyte derived signals during CNS inflammation and recovery
    (Project Head Meissner, Felix )
  - Histopathological platform for analysis of hepatic and renal fibrosis
    (Project Heads Boor, Ph.D., Peter ; Fischer, Hans-Peter ; Franklin, Bernardo ; Kristiansen, Glen ; Longerich, Thomas )
Major Research Instrumentation
- Completed projects
  - mass spectrometer
  - mass spectrometer
International Research Training Groups
- Current projects
  - GRK 2168: Myeloid antigen presenting cells and the induction of adaptive immunity
    (Spokesperson Kurts, Christian )
NFDI technical and methodological consortia
- Current projects
  - National Research Data Infrastructure for Immunology
    (Spokesperson Busse, Christian )

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