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Institution

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Eberhard Karls Universität Tübingen
Interfakultäres Institut für Zellbiologie
Abteilung Immunologie

Address Auf der Morgenstelle 15
72076 Tübingen
Deutschland

GERiT This institution in GERiT

72076 Tübingen

Projects

Research Grants
- Completed projects
Independent Junior Research Groups
- Completed projects
  - Structure-function relationships of Toll-like receptors, key mediators of antiviral innate immunity, in Human Papillomavirus 16 infection and cervical cancer
    (Applicant Weber, Ph.D., Alexander )
Priority Programmes
- Current projects
  - Principles of extra- and intracellular chitin perception by mammalian pattern recognition receptors
    (Applicant Weber, Ph.D., Alexander )
  - STAPHEX II: Dissecting Staphylococcus aureus macrophage exit
    (Applicants Weber, Ph.D., Alexander ; Wolz, Christiane )
- Completed projects
  - Characterization of urinary peptides: In search of MHC-dependent olfactory cues
    (Applicant Rammensee, Hans-Georg )
  - Spezifität und Mechanismus des eukaryotischen 20S/26S Proteasoms (Specificity and mechanism of the eukaryotic 20S/26S proteasome)
    (Applicant Schild, Hansjörg )
Collaborative Research Centres
- Current projects
  - Harnessing molecular vulnerabilities to promote an antitumor immune microenvironment
    (Project Heads Gouttefangeas, Cécile ; Rammensee, Hans-Georg )
- Completed projects
  - Administration and Central Tasks
    (Project Head Rammensee, Hans-Georg )
  - Development of therapeutic antibodies for the elimination of tumor stem cells
    (Project Heads Bühring, Hans-Jörg ; Große-Hovest, Ludger ; Jung, Gundram )
  - Dysfunctional human antigen-specific CD8+ T cells
    (Project Heads Gouttefangeas, Cécile ; Pawelec, Graham )
  - Functional characterization and therapeutic targeting of MyD88 and Interleukin-1 receptor-associated kinases (IRAKs) in lymphoma and leukemia
    (Project Head Weber, Ph.D., Alexander )
  - Geschäftsstelle
    (Project Head Rammensee, Hans-Georg )
  - Immunomonitoring
    (Project Head Gouttefangeas, Cécile )
  - Individual chemo-immunotherapy of peritoneal carcinomatosis
    (Project Heads Königsrainer, Alfred ; Löb, Stefan ; Rammensee, Hans-Georg )
  - Preparative steps for the development of multipeptide vaccines for patients with ovarian cancer
    (Project Heads Rammensee, Hans-Georg ; Staebler, Annette )
  - Selective induction of apoptosis in tumor cells by bispecific antibodies directed to tenascin and the death receptor CD95/Fas/APO-1
    (Project Head Jung, Gundram )
  - SFB 510: Stem Cells and Antigen Recognition in the Hematopoietic System. From Hematopoietic "Stem Cells to Immunotherapy"
    (Spokesperson Rammensee, Hans-Georg )
  - SFB 685: Immunotherapy: Molecular Basis and Clinical Application
    (Spokesperson Rammensee, Hans-Georg )
  - Sleep effects on the initiation, maintenance and recall of T cell memory in humans
    (Project Heads Lange, Tanja ; Rammensee, Hans-Georg )
  - T-cell epitopes for the immunotherapy of urological cancers
    (Project Heads Bedke, Jens ; Stevanovic, Ph.D., Stefan )
  - Tumorassoziierte MHC-I-Liganden auf soliden Tumoren
    (Project Head Stevanovic, Ph.D., Stefan )
  - Untersuchung der Rolle von T-Lymphozyten bei Vitiligo und Voruntersuchungen zur Immuntherapie
    (Project Heads Garbe, Claus ; Rammensee, Hans-Georg )
  - Zwei neue Ansätze zur Tumor-Immuntherapie mit bispezifischen Antikörpern: Charakterisierung und Optimierung in vitro
    (Project Head Jung, Gundram )
Clinical Research Units
- Completed projects
  - Charakterisierung des Betazellversagens
    (Applicant Fritsche, Andreas )
Major Research Instrumentation
- Completed projects
  - Spinning disk confocal microscope for visualizing and quantifying host-bacteria interactions
CRC/Transregios
- Current projects
  - Microbe and host RNA-mediated immune activation in the skin
    (Project Heads Dalpke, Alexander ; Eigenbrod, Tatjana ; Hartl, Dominik ; Weber, Ph.D., Alexander )
  - Platelets as novel contributors to psoriasis skin autoinflammation
    (Project Heads Weber, Ph.D., Alexander ; Weigelin, Bettina )
Research Training Groups
- Completed projects
  - GRK 794: Cellular Mechanisms of Immune-Associated Processes
    (Spokesperson Rammensee, Hans-Georg )
Clusters of Excellence (ExStra)
- Current projects
  - EXC 2124: Controlling Microbes to Fight Infections (CMFI)
    (Spokespersons Brötz-Oesterhelt, Heike ; Ley, Ruth E. ; Peschel, Andreas )
  - EXC 2180: Image-Guided and Functionally Instructed Tumor Therapies (iFIT)
    (Spokespersons Pichler, Bernd ; Rammensee, Hans-Georg ; Walz, Juliane ; Zender, Lars )

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