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Ludwig-Maximilians-Universität München
Fakultät für Chemie und Pharmazie
Department Chemie

Address Butenandtstraße 5-13
81377 München
Deutschland

GERiT This institution in GERiT

81377 München

Projects

Priority Programmes
- Current projects
  - Electroactive MOF Networks
    (Applicants Bein, Thomas ; Clark, Timothy ; Medina-Tautz, Dana-Dina )
- Completed projects
Research Grants
- Current projects
- Completed projects
Research Units
- Current projects
  - Enzymatic generation of double-modified SAM analogues
    (Applicant Rentmeister, Andrea )
  - FOR 5596: Unfolding the potential of S-adenosylmethionine-dependent enzyme chemistry
    (Spokesperson Andexer, Jennifer )
- Completed projects
Independent Junior Research Groups
- Current projects
  - Functional transition metal nitrides
    (Applicant Kloß, Simon David )
  - Structural biology of the hepatitis B virus: from assembly towards design of therapeutics
    (Applicant Schütz, Anne )
- Completed projects
Heisenberg Fellowships
- Completed projects
  - Functional and structural characterization of regulatory nucleic acids and functionalization of protein in Bacilus subtilis
    (Applicant Schneider, Sabine )
Heisenberg Grants
- Completed projects
  - Functional and structural characterization of regulatory nucleic acids and functionalization of protein in Bacilus subtilis
    (Applicant Schneider, Sabine )
WBP Position
- Current projects
  - Carbon-Carbon Bond-Forming Ligand Coupling through Sulfuranes in Organic Synthesis
    (Applicant Saito, Fumito )
  - Translation inhibition during ribotoxic stress mediated by the CAF-1 complex
    (Applicant Müller, Martin )
Collaborative Research Centres
- Current projects
  - Analysis of epigenetic modifications in micro RNAs
    (Project Head Schneider, Sabine )
  - A semi-synthetic nanosystem for programmable control of output based on rational design and directed evolution
    (Project Head Rentmeister, Andrea )
  - Cell-type and activation-specific labelling of different leukocyte populations in vivo by bioorthogonal tagging
    (Project Heads Mootz, Henning D. ; Rentmeister, Andrea )
  - Central Tasks of the Collaborative Research Centre
    (Project Head Carell, Thomas )
  - Characterisation of microtubule glycylation during neuronal differentiation
    (Project Head Kielkowski, Ph.D., Pavel )
  - Chemical Reporters to study O-GlcNAcylation in Epigenetics
    (Project Head Hoffmann-Röder, Anja )
  - Formation and analysis of DNA-protein crosslinks
    (Project Head Carell, Thomas )
  - Integrated Research Training Group
    (Project Heads Carell, Thomas ; Daumann, Lena ; Kaiser, Stefanie ; Zipse, Hendrik )
  - Integrated Research Training Group - Adaptive nanosystems: Principles and applications
    (Project Heads Rentmeister, Andrea ; Salinga, Martin )
  - Molecular mechanism of 5mC oxidation and its implications on chromatin structure and gene regulation
    (Project Head Giehr, Peter Pascal )
  - Molecular mechanism of active demethylation
    (Project Head Carell, Thomas )
  - Oxidative lesions of modified nucleotide bases
    (Project Head Zipse, Hendrik )
  - Quantum Chemical Investigations of Epigenetically Related Enzyme Mechanisms
    (Project Head Ochsenfeld, Christian )
  - SFB 1309: Chemical Biology of Epigenetic Modifications
    (Spokesperson Carell, Thomas )
  - What defines the structure of tRNA? The role of epigenetic modifications and electrostatics quantified by NMR spectroscopy and theory
    (Project Heads Fingerhut, Benjamin ; Schütz, Anne )
- Completed projects
  - Analysis of enzymatic processes using linear-scaling quantum-chemical methods
    (Project Head Ochsenfeld, Christian )
  - Beobachtung einzelner Molekülen in nanoporösen Systemen - von molekularen Funktionselementen zu biofunktionalisierten Nanopartikeln
    (Project Heads Bein, Thomas ; Bräuchle, Christoph )
  - Central Admininistration
    (Project Head Carell, Thomas )
  - Chemo-enzymatic Manipulation of RNA: Sequence-specifity via Cooperative Effects
    (Project Head Rentmeister, Andrea )
  - Combining advanced fluorescence methods and nanoagents
    (Project Head Lamb, Don C. )
  - Concertedness in organic reactions
    (Project Heads Mayr, Herbert ; Ofial, Armin )
  - Conformational switches in viral regulatory proteins
    (Project Head Schütz, Anne )
  - Development and Application of Novel Fluorescent Methods for Investigating the Dynamics of Conformational Fluctuations, Protein Folding, and Dynamics of Living Systems
    (Project Heads Bräuchle, Christoph ; Lamb, Don C. )
  - Dynamics and control of photochemical processes: linking ultrafast dynamics and experimental observables
    (Project Head de Vivie-Riedle, Regina )
  - Dynamics and Intermediates of DNA Base Modification Processes
    (Project Head Carell, Thomas )
  - Dynamik in und mit mesoporösen Nanostrukturen
    (Project Heads Bein, Thomas ; Michaelis, Jens )
  - Einzelmolekülspektroskopische Untersuchung von Protein-Chromophor-Wechselwirkung
    (Project Head Bräuchle, Christoph )
  - Elucidating the interaction of transcription factors with the TBP:DNA complex using single-molecule methods
    (Project Head Lamb, Don C. )
  - Experimental and theoretical investigations of spin-nanostructures built from single atoms
    (Project Heads Ebert, Hubert ; Giessibl, Franz J. )
  - Hochdurchsatzscreening von Katalysatoren und Reaktionen
    (Project Head Trapp, Oliver )
  - In planta-Visualisierung eines Transkriptionsfaktorkomplexes im Translokationsprozess vom Cytoplasma in den Kern
    (Project Heads Tinnefeld, Philip ; Weisshaar, Bernd )
  - Integrated Research Training Group
    (Project Heads Braun, Dieter ; Liedl, Tim ; Ruthardt, Nadia ; Rädler, Joachim ; Tinnefeld, Philip )
  - Kinetic investigations on regioselective and stereoselective metalations of functionalized organic compounds in vitro and by using flow-chemistry
    (Project Head Knochel, Paul )
  - Mechanistic studies of oxidative DNA demethylation and novel photoswitchable peptides for biological applications
    (Project Head Hoffmann-Röder, Anja )
  - Membrane Sensors by DNA Nanotech
    (Project Head Tinnefeld, Philip )
  - Nano-agents for the manipulation of innate immunity
    (Project Head Carell, Thomas )
  - Optische Spektroskopie an einzelnen Donor-Akzeptor-Molekülen in der Frequenz- und Zeitdomäne
    (Project Head Bräuchle, Christoph )
  - Radical Stability in Neutral and Anionic Systems
    (Project Head Zipse, Hendrik )
  - RNA aptamers as sensors for the miR200-family of micro RNAs
    (Project Head Schneider, Sabine )
  - Schlüsselschritte der Biosynthese von Pilzinhaltstoffen
    (Project Head Steglich, Wolfgang )
  - SFB 749: Dynamics and Intermediates of Molecular Transformations
    (Spokesperson Carell, Thomas )
  - Single molecule fluorescence methods for investigating conformational dynamics and allosteric effects in chaperones
    (Project Head Lamb, Don C. )
  - Single Virus Tracing: Visualisierung des Infektionsweges einzelner Viren mit hoher Orts- und Zeitauflösung
    (Project Head Bräuchle, Christoph )
  - Spin Hall Effect in Metallic Heterostructures
    (Project Heads Back, Christian ; Ebert, Hubert ; Woltersdorf, Georg )
  - Structure and conductivity of surfaces on topological insulators
    (Project Heads Ebert, Hubert ; Giessibl, Franz J. )
  - Switchable Mesoporous Nanoconstructs for Controlling Cell Functions in Space and Time
    (Project Head Bein, Thomas )
  - Synthese selektriv metallisierbarer, nanometerskaliger Oligonukleotide
    (Project Head Carell, Thomas )
  - The chemistry of nucleotide excision repair and cellular development
    (Project Head Carell, Thomas )
  - The effect of DNA modifications on the stability and mobility of nucleosomes
    (Project Heads Linser, Ph.D., Rasmus ; Rovó, Petra )
  - Ultradünne funktionale Nanodrähte für elektronische und optische Anwendungen
    (Project Head Bein, Thomas )
  - Verdünnte Ferromagnete und Andreev-Reflektion in Supraleiter/Ferromagnet-Heterostrukturen
    (Project Heads Bayreuther, Günther ; Ebert, Hubert ; Strunk, Christoph )
  - Vielteilchenbeschreibung ferromagnetischer Halbleiter: Korrelationseffekte in elektrischen und magnetischen Eigenschaften
    (Project Heads Ebert, Hubert ; Schliemann, John )
  - Visualisierung des Transports von Nanopartikeln (künstliche Viren) in lebenden Zellen
    (Project Head Bräuchle, Christoph )
Research Fellowships
- Completed projects
Major Research Instrumentation
- Completed projects
CRC/Transregios
- Current projects
  - Chemical biology of intracellular nucleic acid recognition
    (Project Heads Carell, Thomas ; Hornung, Veit )
  - Environmental effects on excited states dynamics: Insights and benchmarks from quantum chemistry
    (Project Heads Ochsenfeld, Christian ; de Vivie-Riedle, Regina )
  - Evolutionary organocatalyst – riboglycosides
    (Project Head Trapp, Oliver )
  - The dynamics of hepatitis B virus morphogenesis and its relevance to persistent infection.
    (Project Heads Schütz, Anne ; Seitz, Ph.D., Stefan )
  - TRR 179: Determinants and dynamics of elimination versus persistence of hepatitis virus infection
    (Spokesperson Bartenschlager, Ralf Friedrich Wilhelm )
- Completed projects
  - Direct DNA and RNA synthesis: From nucleosides over nucleotides to oligomers
    (Project Heads Kaila, Ville ; Ochsenfeld, Christian ; Trapp, Oliver )
  - Integrated Research Training Group
    (Project Heads Braun, Dieter ; Trapp, Oliver )
  - Self-enhanced microfluidic synthesis and polymerization of RNA and DNA
    (Project Heads Braun, Dieter ; Frey, Erwin ; Trapp, Oliver )
  - Subaerial magma-driven hydrothermal systems in the Hadean as physical and chemical factory
    (Project Heads Huber, Claudia ; Scheu, Bettina ; Schmitt-Kopplin, Philippe ; Trapp, Oliver )
WBP Fellowship
- Current projects
  - Pairing Accuracy and Efficiency in a Multi-Reference Excited State Method Applicable in Non-Adiabatic Molecular Dynamics Simulations
    (Applicant Graf, Daniel )
Emmy Noether International Fellowships
- Completed projects
  - 1. Development of a high-throughput screening method for proteome analysis by coupling of capillary electrophoretic methods and microchips with Hadamard transform time-of-flight mass spectrometry 2. Synthesis, application and interaction studies of new tetrahydroporphyrins
    (Applicant Trapp, Oliver )
Research data and software
- Completed projects
  - Überregionale Informationsservices: RADAR Research Data Repositorium
    (Applicants Bein, Thomas ; Helmes, Leni ; Neumair, Bernhard ; Rosemann, Uwe ; Wessjohann, Ludger A. )
Research Training Groups
- Current projects
  - GRK 2338: Targets in Toxicology - Deciphering Therapeutic Targets in Lung Toxicology
    (Spokesperson Gudermann, Thomas )
  - GRK 2620: Ion Pair Effects in Molecular Reactivity
    (Spokesperson Gschwind, Ruth M. )
- Completed projects
  - GRK 441: Chemistry in Interphases - Synthesis, Dynamics, and Application of Polymer-Anchored Active Centers
    (Spokesperson Albert, Klaus )
  - GRK 541: Protein Function at the Atomic Level
    (Spokesperson Buckel, Wolfgang )
  - GRK 1721: Integrated Analysis of Macromolecular Complexes and Hybrid Methods in Genome Biology
    (Spokesperson Hopfner, Karl-Peter )
  - GRK 2062: Molecular Principlas of Synthetic Biology
    (Spokesperson Jung, Kirsten )
  - GRK 2223: Protein Complex Assembly (PROCOMPAS)
    (Spokesperson Mendel, Ralf R. )
International Research Training Groups
- Current projects
  - GRK 2678: Functional pi-systems: Activation, Interaction and Applications (pi-Sys)
    (Spokesperson Studer, Armido )
- Completed projects
  - GRK 2027: New Trends in Molecular Activation and Catalysis
    (Spokesperson Hahn, F. Ekkehardt )
Major Instrumentation Initiatives
- Current projects
  - Fast and integrated fluorescence lifetime microscopy
Clusters of Excellence
- Completed projects
  - EXC 4: Nanosystems Initiative Munich (NIM)
    (Spokespersons Bein, Thomas ; Feldmann, Jochen )
  - EXC 114: Munich Center for Integrated Protein Science (CIPSM)
    (Spokesperson Carell, Thomas )
  - EXC 158: Munich-Centre for Advanced Photonics (MAP)
    (Spokesperson Krausz, Ph.D., Ferenc )
Clusters of Excellence (ExStra)
- Current projects
  - EXC 2089: e-conversion
    (Spokespersons Bein, Thomas ; Heiz, Ulrich ; Reuter, Karsten )
  - EXC 2094: ORIGINS: From the Origin of the Universe to the First Building Blocks of Life
    (Spokespersons Burkert, Andreas ; Paul, Stephan )
NFDI technical and methodological consortia
- Current projects
  - NFDI4Chem – Chemistry Consortium in the NFDI
    (Spokesperson Steinbeck, Christoph )

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