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Institution

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Deutsches Krebsforschungszentrum (DKFZ)
Forschungsschwerpunkt Zell- und Tumorbiologie
Abteilung Molekulare Embryologie

Address Im Neuenheimer Feld 280
69120 Heidelberg
Deutschland

GERiT This institution in GERiT

69120 Heidelberg

Projects

Research Grants
- Current projects
  - Role of secreted factors regulating canonical and noncanonical WNT signalling in cartilage-bone specification of chondrocytes
    (Applicant Diederichs, Solvig )
- Completed projects
  - Analyse der Genregulation in Synexpressionsgruppen
    (Applicant Niehrs, Ph.D., Christof )
  - Characterization of a 5-formylcytosine chromocenter in Xenopus embryos
    (Applicant Niehrs, Ph.D., Christof )
  - Die biologische Rolle und der Wirkungsmechanismus von R-sponding2
    (Applicant Niehrs, Ph.D., Christof )
  - Role of NEIL DNA glycosylases in DNA demethylation and differentiation
    (Applicant Niehrs, Ph.D., Christof )
  - System level analysis of the BMP4 synexpression groups
    (Applicant Niehrs, Ph.D., Christof )
Priority Programmes
- Completed projects
  - Analyse der Genregulation in Synexpressionsgruppen
    (Applicant Niehrs, Ph.D., Christof )
  - Role of Gadd45 in pluripotency and murine embryogenesis
    (Applicant Niehrs, Ph.D., Christof )
  - Systematische Analyse embryonaler Genexpression in Xenopus
    (Applicant Niehrs, Ph.D., Christof )
Research Units
- Completed projects
  - Roles and mechanisms of asymmetric LRP6 localization in Xenopus embryonic cells
    (Applicant Niehrs, Ph.D., Christof )
Collaborative Research Centres
- Current projects
  - Integrated Research Training Group
    (Project Heads Dahm, Ralf ; Niehrs, Ph.D., Christof )
  - Mechanism and biological function of mammalian DNA Poly-ADP-ribosylation
    (Project Head Niehrs, Ph.D., Christof )
  - Post-transcriptional mechanisms in synaptic plasticity and memory consolidation: Role of mRNA stability
    (Project Heads Lutz, Beat ; Niehrs, Ph.D., Christof )
  - Role of DDX56 in GSK3β regulation during Wnt signaling
    (Project Head Niehrs, Ph.D., Christof )
- Completed projects
  - Functional characterization of a novel Wnt regulator in the central nervous system
    (Project Heads Niehrs, Ph.D., Christof ; Sirrenberg-Cruciat, Cristina-Maria )
  - Role of NEIL DNA glycosylases in DNA demethylation and base excision repair
    (Project Head Niehrs, Ph.D., Christof )
  - Role of Wnt signaling in embryonic neural stem cells
    (Project Head Niehrs, Ph.D., Christof )
Major Research Instrumentation
- Completed projects
Research Training Groups
- Current projects
  - GRK 2859: R-loop Regulation in Robustness and Resilience
    (Spokesperson Luke, Ph.D., Brian )
- Completed projects
  - GRK 484: Signalling Systems and Gene Expression in Developmental Model Systems
    (Spokesperson Pollerberg, Gabriele Elisabeth )
  - GRK 791: Neural Developmental and Degenerative Processes: Basic Research and Clinical Implications
    (Spokesperson Monyer, Hannah )

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