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Leibniz-Institut für Arbeitsforschung an der TU Dortmund (IfADo)
Forschungsbereich ambulante Patientenversorgung und translationale Wissenschaft

Address Ardeystraße 67
44139 Dortmund
Deutschland

GERiT This institution in GERiT

44139 Dortmund

Projects

Research Grants
- Current projects
  - Progression of chronic liver disease: Defining the contributions of hepatocytic JNK expression and gut microbiota
    (Applicant Trautwein, Christian )
- Completed projects
  - Molekulare Analyse zur Rolle von Cyclin E für den G0/S-Phase Zellzyklusübergang und die maligne Transformation der Hepatozyten
    (Applicant Liedtke, Christian )
  - Rolle TNF alpha und Fas-abhängiger Signalwege für die Leber
    (Applicant Trautwein, Christian )
Collaborative Research Centres
- Current projects
  - Functional impact of risk factors for disease progression within the gut-liver axis
    (Project Heads Candels, Lena ; Trautwein, Christian )
- Completed projects
  - A physiologically-based model of bile acid metabolism
    (Project Heads Blank, Ph.D., Lars ; Neumann, Ulf P. ; Trautwein, Christian )
  - Bedeutung IL6/gpl30-abhängiger Signalkaskaden für die Leber
    (Project Head Trautwein, Christian )
  - Lebertransplantation bei viraler Hepatitis: Ätiologie, Pathogenese, Prognose und Prophylaxe der Reinfektion
    (Project Heads Manns, Michael Peter ; Tillmann, Hans-Ludger ; Trautwein, Christian )
  - Multi-functional microgels targeted towards inflammatory bowel disease (IBD)
    (Project Heads Elling, Lothar ; Kühne, Alexander ; Sellge, Gernot ; Strnad, Pavel ; Trautwein, Christian )
  - Role of gp130-dependent signalling in hepatocytes for the regulation of immune responses in local and systemic models of inflammation
    (Project Head Trautwein, Christian )
  - The Role of TNF and Fas-mediated signalling in models of inflammatory liver injury
    (Project Heads Liedtke, Christian ; Trautwein, Christian )
CRC/Transregios
- Completed projects
  - Central Tasks of the Collaborative Research Centre
    (Project Head Trautwein, Christian )
  - Inflammasome activation during cholestatic liver injury: A trigger of fibrosis progression
    (Project Heads Trautwein, Christian ; Wree, Alexander )
  - Inflammatory and cell-death-related pathways in liver fibrosis: Cell-type specific approaches to novel therapies
    (Project Heads Lüdde, Ph.D., Tom ; Trautwein, Christian )
  - Treatment of liver fibrosis through inhibition of the Cyclin E1/Cdk2 kinase complex
    (Project Heads Liedtke, Christian ; Nevzorova, Ph.D., Yulia ; Trautwein, Christian )
  - TRR 57: Organ Fibrosis: From Mechanisms of Injury to Modulation of Disease
    (Spokesperson Trautwein, Christian )
Research Training Groups
- Current projects
  - GRK 2375: Tumor-Targeted Drug Delivery
    (Spokesperson Kiessling, Fabian )
International Research Training Groups
- Completed projects
  - GRK 1508: Arterial Remodelling
    (Spokesperson Bernhagen, Jürgen )

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