Professor Dr. Claus Seidel

Address Heinrich-Heine-Universität Düsseldorf
Institut für Physikalische Chemie
Lehrstuhl für Molekulare Physikalische Chemie
Universitätsstraße 1
40225 Düsseldorf

Projects

As Applicant
- Current projects
  - Molecular mechanisms and physiological functions of DNA damage condensates (Priority Programmes)
- Completed projects
  - Design und Charakterisierung von Hairpintwinribozymen zur RNA-Reparatur (Research Grants)
  - Improving the catalytic activity of a thermostable anthranilate phosphoribosyl transferase by directed evolution (Priority Programmes)
  - Single molecule fluorescence studies of the structure and dynamics of chromatin complexes (Einzelmolekül-Fluoreszenzuntersuchungen zur Struktur und Dynamik von Chromatinkomplexen) (Priority Programmes)
  - Single molecule fluorescence studies of the structure and dynamics of chromatin complexes (Priority Programmes)
  - Improving the catalytic activity of a thermostable anthranilate phosphoribosyl transferase by directed evolution (Priority Programmes)
  - Single-molecule fluorescence spectroscopy to study structure and conformational dynamics of model proteins and the transporter BetP from Corynebacterium glutamicum (Research Grants)
  - Single-molecule fluorescence analysis of the temperature dependent structure and dynamics of an RNA thermometer: consequences for its molecular function (Priority Programmes)
  - Mechanism of opening and closing of nucleosomes: single molecule fluorescence studies (Research Grants)
  - Function of lipase-specific foldase for folding and secretion of a lipase from Pseudomonas aeruginosa (Research Grants)
  - Dynamics of human Guanylate Binding Proteins: implications for their structure and oligomerisation (Research Grants)
As Leader
- Completed projects
  - STED-MFIS Mikroskop (Major Research Instrumentation)
  - High resolution Microscope for Multi-parameter Fluorescence Image Spectroscopy (Major Research Instrumentation)
As Participating Researcher
- Completed projects
  - GRK 2482: Modulation of Intersystem Crossing - ModISC (Research Training Groups)
As Project Head
- Current projects
  - Structure, dynamics and interactions of proteins during membrane association and dissocia-tion studied by hp-FRET (Collaborative Research Centres)
  - Transport von CLAVATA Rezeptoren und Signalmodifikatoren zwischen Membranen (Collaborative Research Centres)
- Completed projects
  - Einfluss mechanischer Kräfte auf die photochemischen Primärprozesse polymergebundener Chromophore (Collaborative Research Centres)
  - Fluorescence spectroscopic analysis of the structure, transport and interactions of proteins relevant for cellular differentiation (Collaborative Research Centres)
  - Steigerung der Signalstärke und Photostabilität von Fluorophoren bei der Einzelmolekülspektroskopie (Collaborative Research Centres)
  - Structural models and conformational dynamics of the G protein coupled bile acid receptor TGR5 (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Improvement of the central microscopy research infrastructure Center for Advanced Imaging (CAi) at Heinrich Heine University Düsseldorf (Core Facilities)