Project Details
Projekt
Enhanced thrombotic risk and myocardial dysfunction of the infarcted heart in CKD (M05)
Subject Area
Cardiology, Angiology
Term
since 2018
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 322900939
We recently revealed a maladaptive preconditioning of the heart in CKD towards adverse cardiac remodeling after myocardial infarction. Furthermore, CKD patients display increased thrombotic risk. This project will study alterations of regulatory processes in the heart post-myocardial infarction in CKD. Also, it will examine the effect of CKD on platelet responses in relation to the increased thrombotic risk along with enhanced bleeding risk in patients with CKD. Combined, it will provide novel insights and potential novel therapeutic strategies to target increased cardiovascular risk in CKD patients.
DFG Programme
CRC/Transregios
Applicant Institution
Rheinisch-Westfälische Technische Hochschule Aachen
Project Heads
Professor Dr. Nikolaus Albert Helmut Marx; Dr. Heidi Noels, Ph.D.
