Project Details

Professor Dr. Mario Mörl

Address Universität Leipzig
Institut für Biochemie
Arbeitsgruppe Biochemie und Molekularbiologie
Brüderstraße 34
04103 Leipzig

Projects

As Applicant
- Current projects
  - High-throughput structure probing of RNA based on specific ligation of cyclo-phosphate ends combined with deep sequencing (Research Grants)
  - Miniaturized armless tRNAs – function, interaction, modifications (Research Grants)
  - Design of synthetic RNase-resistant RNA structures and their integration in novel riboswitch constructs to regulate mRNA stability (Research Grants)
  - CCA-adding enzymes with increased substrate affinities: strategies and consequences for adaptation to RNA substrates (Research Grants)
- Completed projects
  - Analysis of structure-function relation in nucleotidyltransferases (Research Grants)
  - In vitro recapitulation of the evolution of tRNA nucleotidyltransferases (CCA-adding enzymes) (Priority Programmes)
  - tRNA editing in S. cerevisiae: Isolation and Identification of the responsible nucleotidyltransferase (Research Grants)
  - Co-evolution of bizarre armless tRNAs and their maturation enzymes in Enoplea (Research Grants)
  - Regulatory function of the tRNA 3'-end in E. coli (Research Grants)
  - Evolution of Chemical Modifications: from tRNAs to Transcriptome-Wide Surveys (Priority Programmes)
  - Unusual RNA-polymerases: reaction mechanism and substrate specificity of tRNA nucleotidyltransferases (Research Grants)
  - Synthetic riboswitches: design of multi-ligand switches and novel regulatory principle (Research Grants)
As Leader
- Completed projects
  - Autoradiographie- und Fluoreszenzimager (Major Research Instrumentation)

Servicenavigation

Hauptnavigation

Professor Dr. Mario Mörl

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Mario Mörl

Additional Information

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