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Project Details

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Professorin Dr. Esther Lutgens

Address Mayo Clinic
Division of Cardiovascular Diseases
200 First Street SW
Rochester MN 55905
USA

Projects

As Applicant
- Completed projects
  - Function of co-stimulatory pathways in atheroslerosis (Research Units)
As Project Head
- Current projects
  - Epigenetic regulation of T cell activation via the polycomb repressive complex 2 in atherosclerosis (Collaborative Research Centres)
  - The CD40/CD40L-axis in aortic aneurysm: defining immune cell interactions and therapeutic targets (CRC/Transregios)
- Completed projects
  - The Effect of Hypercholesterolemia on Co-Stimulatory Molecule Function: From Stem and Progenitor Cells to the Mature Immune System (Collaborative Research Centres)
As Host
- Completed projects
  - Regulation of microRNA-302a in human and mouse macrophages after stimulation with modified low density lipoproteins. The main focus of the research is to explore whether microRNA-302a contributes to the maintenance of cholesterol homeostasis and therefore has an important role in the pathogenesis of atherosclerosis (Research Fellowships)

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