A therapeutic approach to enhance innate defense mechanisms against toxins and venoms - mast cell proteases to the rescue

Antragsteller Professor Dr. Martin Metz

Fachliche Zuordnung Dermatologie

Förderung Förderung von 2009 bis 2015

Projektkennung Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 125440970

Erstellungsjahr 2019

Keine Zusammenfassung vorhanden

Mast cells orchestrate type 2 immunity to helminths through regulation of tissue derived cytokines. PNAS 2012;109:6644-9
Hepworth, Matthew R.; Daniłowicz-Luebert, Emilia; Rausch, Sebastian; Metz, Martin; Klotz, Christian; Maurer, Marcus & Hartmann, Susanne
A beneficial role for immunoglobulin E in host defense against honeybee venom. Immunity 2013;39:963-75
Marichal, Thomas; Starkl, Philipp; Reber, Laurent L.; Kalesnikoff, Janet; Oettgen, Hans C.; Tsai, Mindy; Metz, Martin & Galli, Stephen J.
Mast Cells Limit the Exacerbation of Chronic Allergic Contact Dermatitis in Response to Repeated Allergen Exposure. J Immunol, 2016;197:4240-4246
Gimenez-Rivera, Vladimir-Andrey; Siebenhaar, Frank; Zimmermann, Carolin; Siiskonen, Hanna; Metz, Martin & Maurer, Marcus
Human Mast Cell Tryptase Is a Potential Treatment for Snakebite Envenoming Across Multiple Snake Species. Front Immunol, 2018; 9:1532
Anderson, Elizabeth; Stavenhagen, Kathrin; Kolarich, Daniel; Sommerhoff, Christian P.; Maurer, Marcus & Metz, Martin

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