Die Rolle von Exosomen und sekretorischen Lysosomen in der Resistenz von Lymphomen und Leukämien

Applicant Professor Dr. Gerald Wulf

Subject Area Hematology, Oncology

Term from 2009 to 2014

Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 128165491

Final Report Year 2014

Final Report Abstract

No abstract available

Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3. Proc Natl Acad Sci USA. 2011 Sep 13;108(37):15336-41
Aung T, Chapuy B, Vogel D, Wenzel D, Oppermann M, Lahmann M, Weinhage T, Menck K, Hupfeld T, Koch R, Trümper L, Wulf GG
Tyrosinekinase inhibition facilitates cooperation of transcription factor SALL4 and ABC transporter A3 towards intrinsic CML cell drug resistance. BrJ Haematol. 2013 Apr;161(2):204-13
Hupfeld T, Chapuy B, Schräder V, Beutler M, Veltkamp C, Koch R, Cameron S, Aung T, Haase D, Larosee P, Truemper L, Wulf GG
(See online at https://doi.org/10.1111/bjh.12246)
Populational equilibrium through exosome-mediated Wnt signaling in tumor progression of diffuse large B-cell lymphoma. Blood blood-2013-08-523886; published online February 21, 2014
Raphael Koch, Martin Demant, Thiha Aung, Nina Diering, Anna Cicholas, Bjoem Chapuy, Dirk Wenze, Marlen Lahmann, Annemarie Güntsch, Christina Kiecke, Sabrina Becker, Timo Hupfeld, Vivek Venkataramani, Marita Ziepert, Lennart Opitz, Wolfram Klapper, Lorenz Trümper, Gerald G. Wulf
(See online at https://doi.org/10.1182/blood-2013-08-523886)