Die Rolle von Exosomen und sekretorischen Lysosomen in der Resistenz von Lymphomen und Leukämien

• Applicant: Professor Dr. Gerald Wulf
• Subject Area: Hematology, Oncology
• Term: from 2009 to 2014
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 128165491

• Final Report Year: 2014

No abstract available

Publications

• Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3. Proc Natl Acad Sci USA. 2011 Sep 13;108(37):15336-41
  Aung T, Chapuy B, Vogel D, Wenzel D, Oppermann M, Lahmann M, Weinhage T, Menck K, Hupfeld T, Koch R, Trümper L, Wulf GG
  
• Tyrosinekinase inhibition facilitates cooperation of transcription factor SALL4 and ABC transporter A3 towards intrinsic CML cell drug resistance. BrJ Haematol. 2013 Apr;161(2):204-13
  Hupfeld, Timo; Chapuy, Bjoern; Schrader, Verena; Beutler, Markus; Veltkamp, Christian; Koch, Raphael; Cameron, Silke; Aung, Thiha; Haase, Detlef; LaRosee, Paul; Truemper, Lorenz & Wulf, Gerald G.
  
• Populational equilibrium through exosome-mediated Wnt signaling in tumor progression of diffuse large B-cell lymphoma. Blood blood-2013-08-523886; published online February 21, 2014
  Koch, Raphael; Demant, Martin; Aung, Thiha; Diering, Nina; Cicholas, Anna; Chapuy, Bjoern; Wenzel, Dirk; Lahmann, Marlen; Güntsch, Annemarie; Kiecke, Christina; Becker, Sabrina; Hupfeld, Timo; Venkataramani, Vivek; Ziepert, Marita; Opitz, Lennart; Klapper, Wolfram; Trümper, Lorenz & Wulf, Gerald G.