GRK 1644: Skalenprobleme in der Statistik
Mathematik
Zusammenfassung der Projektergebnisse
This research training group (RTG) focused on “Scaling Problems in Statistics” as a general framework for developing, extending and applying statistical methodology related to scaling problems. In a broad sense, the notion of scale and associated scaling problems can be understood as an encompassing concept for challenges in empirical analysis where the units of observation behave differently when studying them on different scales. This implies that the measurement scale, and in particular the central properties of resolution and extent, have to be taken into account in statistical analyses. Thereby scales can represent very different concepts, ranging from spatial and temporal scales as the most obvious examples, over different levels of aggregation (e.g. from individuals over households to communities or states), to different levels of genetic information (e.g. in a functional scale from single base pairs over genes to pathways of genes). In this RTG, we have been treating scaling as a particular type of contextual information that has to be taken into account appropriately to provide meaningful results for research questions, such as “How does the association of animal and plant abundance depend on ecological conditions?”, “What impact has the price of one product on that of another?” or “How does genetic variation impact susceptibility towards a specific disease or the prediction of a genetically affected trait?” In all these cases, the result crucially depends on the scale chosen for the statistical analysis. Statistical methodology formed the core of the RTG, providing the interface between the considered areas of application (ecology, economics, genetics). This setup allowed us to stimulate methodological innovations based on challenging applications, to transfer general methodological innovations to the applied areas, and to foster the transfer of methods between the different areas of application. The methodological framework for the RTG was formed by mixed models, spatial statistics and distributional regression, roughly corresponding to the notions of hierarchical scales (mixed models), spatial scales (spatial statistics), and the measurement scale (distributional regression), respectively. For some specific projects, additional methodological topics such as networks or kernel regression were considered in addition. The interdisciplinarity of the research agenda of the RTG was also well reflected in the qualification program. The first core element, introductions to mixed models and spatial statistics, provided the PhD students with advanced knowledge in statistical methods dealing with scaling problems. Building on this common ground, further subjects were introduced in the form of specialization courses, research colloquia, and research seminars. A further important ingredient in qualification were courses on key competencies, including mandatory courses on “Diversity Competence”, “Good Scientific Practice” and “Collecting and Archiving Research Data”. Based on the experience from two successful funding phases and three cohorts of PhD students, we have convincing evidence for the stimulating environment that an interdisciplinary group with a methods-driven research and qualification agenda provides for young scientists. The PhD alumni of the RTG report very positively about the experiences they gained from their work in the RTG and in particular highlight the relevance of interdisciplinary collaboration and communication for their future careers in academia as well as in companies. We were able to develop important and innovative research results, where the interdisciplinary setup was stimulating the development of methods via exposure to challenging applied research problems on the one hand and the transfer of novel methods to applications on the other hand.
Projektbezogene Publikationen (Auswahl)
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(2011), Coverage of exon-targeted sequencing, in: C. Hemmelmann, P. Ahnert, R. Foraita, A. Groÿhennig, A. Scherag & K.E. Biebler (Eds.), Biometrische Aspekte der Genomanalyse 4. Next generation sequencing data analysis, 91-97, Shaker, ISBN 9783844001556
Freytag, S., Sohns, M. & Bickeböller, H.
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(2012), A novel kernel for correcting size bias in the logistic kernel machine test with an application to rheumatoid arthritis, Human Heredity 74: 97-108
Freytag, S., Bickeböller, H., Amos, C.I., Kneib, T. & Schlather, M.
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(2012), Effects of habitat isolation and predation pressure on an arboreal food-web, Community Ecology 13: 82-87
Herrmann, J., Kormann, U., Schüepp, C., Stocker, Y., Herzog, F. & Entling, M.
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(2012), Forest monitoring for REDD+: challenges in mapping forest carbon, in: L. Fehrman & C. Kleinn (Eds.), Forest in Climate Change Research and Policy: The Role of Forest Management and Conservation in a Complex International Setting. Proceedings of the 2nd International DAAD Workshop December 2011, Pietermaritzburg and Durban, South Africa, 129-136, Cullivier Verlag, Göttingen
Mundhenk, P.
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(2012), Instant trend-seasonal decomposition of time series with splines, Courant Research Centre Poverty, Equity and Growth - Discussion Papers 131: 1-26
Rosales, F. & Krivobokova, T.
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(2012), Intrinsically weighted means of marked point processes
Malinowski, A., Schlather, M. & Zhang, Z.
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(2012), Parsimony-based pedigree analysis and individual-based landscape genetics suggest topography to restrict dispersal and connectivity in the endangered capercaillie, Biological Conservation 152: 241-252
Kormann, U., Gugerli, F., Ray, N., Excoffier, L. & Bollmann, K.
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(2013), A network-based kernel machine test for the identification of risk pathways in genome-wide association studies, Human Heredity 76: 64-75
Freytag, S., Manitz, J., Schlather, M., Kneib, T., [...] & Bickeböller, H.
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(2013), Bayesian outbreak detection algorithm for monitoring reported cases of campylobacteriosis in Germany, Biometrical Journal 55: 509-526
Manitz, J. & Höhle, M.
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(2013), Comparison of three summary statistics for ranking genes in genome-wide association studies, Statistics in Medicine
Freytag, S. & Bickeböller, H.
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(2013), Enhanced structural complexity index: An improved index for describing forest structural complexity, Open Journal of Forestry 3: 23-29
Beckschäfer, P., Mundhenk, P., Kleinn, C., Ji, Y., Yu, D.W. & Harrison, R.D.
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(2013), Estimating predition error in mixed models, in: V.M.R.Muggeo, V. Capursi, G. Boscaino & G. Lovison (Eds.), Proceedings of the 28th International Workshop on Statistical Modelling, vol. 1, 363-368
Säfken, B., Greven, S. & Kneib, T.
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(2013), Financial models of interaction based on marked point processes and Gaussian fields, Ph.D. thesis, Georg-August-Universität Göttingen
Malinowski, A.
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(2013), Friends or foes? Interplay of facilitation and competition depends on the interaction between abiotic stress and ontogenetic stage, Plant Ecology 214: 1485-1492
Beduschi, T. & Castellani, T.T.
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(2013), The expected linkage disequilibrium infinite populations revisited
Ober, U., Malinowski, A., Schlather, M. & Simianer, H.
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(2014), A unifying approach to the estimation of the conditional akaike information in generalized linear mixed models, Electronic Journal of Statistics 8: 201-225
Säfken, B., Kneib, T., van Waveren, C.S. & Greven, S.
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(2014), BIOFRAG - a new database for analyzing BIOdiversity responses to forest FRAGmentation, Ecology and Evolution 4: 1524-1537
Pfeifer, M., [...], Kormann, U., Scherber, C., Tscharntke, T., Tyre, A.J., Urbina Cardona, J.N.,Vasconcelos, H.L. et al.
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(2014), Coverage and efficiency in current SNP chips, European Journal of Human Genetics 22: 1124-1130
Ha, N.T., Freytag, S. & Bickeböller, H.
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(2014), Kernel methods for genes and networks to study genome-wide associations of lung cancer and rheumatoid arthritis, Ph.D. thesis, Georg-August-Universität Göttingen
Freytag, S.
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(2014), Kernel score statistic for dependent data, BMC Proceedings 8: S41
Malzahn, D., Friedrichs, S., Rosenberger, A. & Bickeböller, H.
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(2014), Statistical inference for max-stable processes by conditioning on extreme events, Advances in Applied Probability 46: 478-495
Engelke, S., Malinowski, A., Oesting, M. & Schlather, M.
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(2014), Statistical inference for propagation processes on complex networks, Ph.D. thesis, Georg-August-Universität Göttingen
Manitz, J.
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(2015), A scale-corrected comparison of linkage disequilibrium levels between genic and non-genic regions, PLOS ONE 10: e0141216+
Berger, S., Schlather, M., de los Campos, G., Weigend, S., Preisinger, R., Erbe, M. & Simianer, H.
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(2015), Effectiveness of shrinkage and variable selection methods for the prediction of complex human traits using data from distantly related individuals, Annals of Human Genetics 79: 122-135
Berger, S. & Pérez-Rodrlos Campos, G.
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(2015), Estimation of Hüsler-Reiss distributions and Brown-Resnick processes, Journal of the Royal Statistical Society: Series B (Statistical Methodology) 77: 239-265
Engelke, S., Malinowski, A., Kabluchko, Z. & Schlather, M.
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(2015), Harnessing the biodiversity value of Central and Eastern European farmland, Diversity and Distributions 21: 722-730
Sutcliffe, L.M.E., Batáry, P., Kormann, U., [...] & Tscharntke, T.
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(2015), Hedgerows have a barrier effect and channel pollinator movement in the agricultural landscape, Journal of Landscape Ecology 8
Klaus, F., Bass, J., Marholt, L., Müller, B., Klatt, B. & Kormann, U.
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(2015), Integrating remotely sensed data into forest resource inventories, Ph.D. thesis, Georg-August-Universität Göttingen
Mundhenk, P.
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(2015), Local and landscape management drive trait-mediated biodiversity of nine taxa on small grassland fragments, Diversity and Distributions 21: 1204-1217
Kormann, U., Rösch, V., Batáry, P., Tscharntke, T., Orci, K.M., Samu, F. & Scherber, C.
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(2015), Model choice and variable selection in mixed & semiparametric models, Ph.D.thesis, Georg-August-Universität Göttingen
Säfken, B.
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(2015), Modeling microbial growth and dynamics, Applied Microbiology and Technology 99
Esser, D.S., Leveau, J.H.J. & Meyer, K.M.
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(2015), Regional heterogeneity, geography and agglomeration effects in efficiency analysis: The case of dairy farming in Europe, Ph.D. thesis, Georg-August-Universität Göttingen
Castro Medina, D.M.
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(2015), Scale dependence of pollinator community turnover and tritrophic interactions in changing landscapes, Ph.D. thesis, Georg-August-Universität Göttingen
Beduschi, T.
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(2015), Scale effects on genomic modelling and prediction, Ph.D. thesis, Georg-August-Universität Göttingen
Berger, S.
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(2015), Scale-dependent management of biodiversity and ecosystem processes in fragmented landscapes, Ph.D. thesis, Georg-August-Universität Göttingen
Kormann, U.
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(2015), Sixty-seven years of land-use change in Southern Costa Rica, PLOS ONE 10: e0143554+
Zahawi, R.A., Duran, G. & Kormann, U.
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(2015), Spatial scales of interactions among bacteria and between bacteria and the leaf surface, FEMS Microbiology Ecology 91
Esser, D.S., Leveau, J.H.J., Meyer, K.M. & Wiegand, K.
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(2015), Stochastic models in population genetics: The impact of selection and recombination, Ph.D. thesis, Georg-August-Universität Göttingen
Brink-Spalink, R.
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(2015), The influence of scale on the measurement of the vertical price transmission, Ph.D. thesis, Georg-August-Universität Göttingen
Tifaoui, S.
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(2015), Using multi-level generalized path analysis to understand herbivore and parasitoid dynamics in changing landscapes, Landscape Ecology 30:1975-1986
Beduschi, T., Tscharntke, T. & Scherber, C.
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(2016), A robust statistical approach to select adequate error distributions for financial returns, Journal of Applied Statistics 44: 137-161
Hambuckers, J. & Heuchenne, C.
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(2016), Behavioral studies on the use of open water basins by American mink (neovison vison), Journal of Veterinary Behavior: Clinical Applications and Research 13: 19-26
Schwarzer, A., Bergmann, S., Manitz, J., Küchenhoff, H., Erhard, M. & Rauch, E.
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(2016), Corridors restore animal-mediated pollination in fragmented tropical forest landscapes, Proceedings of the Royal Society B 283: 20152347
Kormann, U., Scherber, C., Tscharntke, T., Klein, N., Larbig, M., Valente, J.J., Hadley, A.S. & Betts, M.G.
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(2016), Empirical Bayesian smoothing splines for signals with correlated errors: Methods and applications, Ph.D. thesis, Georg-August-Universität Göttingen
Rosales, F.
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(2016), Epidemiological and ecological characterization of the EHEC O104:H4 outbreak in Hamburg, Germany, 2011, PLOS ONE 11: e0164508+
Tahden, M., Manitz, J., Baumgardt, K., Fell, G., Kneib, T. & Hegasy, G.
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(2016), Estimating the out-of-sample predictive ability of trading rules: A robust bootstrap approach, Journal of Forecasting 35: 347-372
Hambuckers, J. & Heuchenne, C.
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(2016), NetOrigin: Origin estimation for propagation processes on complex networks
Manitz, J. & Harbering, J.
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(2016), Smoothing parameter and model selection for general smooth models, Journal of the American Statistical Association 111: 1548-1563
Wood, S.N., Pya, N. & Säfken, B.
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(2016), Spillover of arthropods from cropland to protected calcareous grassland - the neighbouring habitat matters, Agriculture, Ecosystems & Environment 235: 127-133
Madeira, F., Tscharntke, T., Elek, Z., Kormann, U., Pons, X., Rösch, V., Samu, F., Scherber, C. et al.
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(2017), Effect separation in regression models with multiple scales, Ph.D. thesis, Georg-August-Universität Göttingen
Thaden, H.
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(2017), Genealogies of two linked neutral loci after a selective sweep in a large population of stochastically varying size, Advances in Applied Probability 49: 279-326
Brink-Spalink, R. & Smadi, C.
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(2017), How can seed removal rates of zoochoric tree species be assessed quickly and accurately?, Forest Ecology and Management 403: 152-160
Hambuckers, J., Dauvrin, A., Trolliet, F., Evrard, Q., Forget, P.M. & Hambuckers, A.
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(2017), Integrating multivariate conditionally autoregressive spatial priors into recursive bivariate models for analyzing environmental sensitivity of mussels, Spatial Statistics 22: 419-433
Thaden, H., Pata, M.P., Klein, N., Cadarso-Suárez, C. & Kneib, T.
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(2017), kangar00: Kernel approaches for nonlinear genetic association regression
Manitz, J., Friedrichs, S., Burger, P., Hofner, B., Ha, N.T., Freytag, S. & Bickeböller, H.
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(2017), Kernel-based pathway approaches for testing and selection, Ph.D. thesis, Georg-August-Universität Göttingen
Friedrichs, S.
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(2017), Pathway-based kernel boosting for the analysis of genome-wide association studies, Computational and Mathematical Methods in Medicine 2017: 1-17
Friedrichs, S., Manitz, J., [...], Kneib, T., Bickeböller, H. & Hofner, B.
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(2017), Scales of bacterial interactions on the leaf surface, Ph.D. thesis, Georg-August-Universität Göttingen
Esser, D.S.
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(2017), Scaling of animal communities: From local and landscape to global processes, Ph.D. thesis, Georg-August-Universität Göttingen
Udy, K.
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(2017), Source estimation for propagation processes on complex networks with an application to delays in public transportation systems, Journal of the Royal Statistical Society: Series C (Applied Statistics) 66: 521-536
Manitz, J., Harbering, J., Schmidt, M., Kneib, T. & Schöbel, A.
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(2017), Temporary sales prices and asymmetric price transmission, Agribusiness 33: 85-97
Tifaoui, S. & von Cramon-Taubadel, S.
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(2017), The role of heterogeneity in spatial plant population dynamics, Ph.D. thesis, Georg-August-Universität Göttingen
van Waveren, C.S.
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(2018), A Markov-switching generalized additive model for compound Poisson processes, with applications to operational loss models, Quantitative Finance 18: 1679-1698
Hambuckers, J., Kneib, T., Langrock, R. & Silbersdorff, A.
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(2018), Adaptive non-parametric estimation of mean and autocovariance in regression with dependent errors
Serra, P., Krivobokova, T. & Rosales, F.
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(2018), Dualities and genealogies in stochastic population models, Ph.D. thesis, Georg-August-Universität Göttingen
Mach, T.
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(2018), Ensemble classification of individual Pinus crowns from multispectral satellite imagery and airborne LiDAR, International Journal of Applied Earth Observation and Geoinformation 65: 12-23
Kukunda, C.B., Duque-Lazo, J., González-Ferreiro, E., Thaden, H. & Kleinn, C.
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(2018), Health care service provision in Europe and regional diversity: a stochastic metafrontier approach, Health Economics Review 8
Schley, K.
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(2018), Heterogeneity of long-run technical efficiency of german dairy farms: A Bayesian approach, Journal of Agricultural Economics 69: 58-75
Skevas, I., Emvalomatis, G. & Brümmer, B.
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(2018), Improving health care service provision by adapting to regional diversity: An efficiency analysis for the case of Germany, Health Policy 122: 293-300
Herwartz, H. & Schley, K.
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(2018), Local and landscape effects on arthropod communities along an arable-urban gradient, Ph.D. thesis, Georg-August-Universität Göttingen
Reininghaus, H.
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(2018), Productivity growth measurement and decomposition under a dynamic inefficiency specification: The case of German dairy farms, European Journal of Operational Research 271: 250-261
Skevas, I., Emvalomatis, G. & Brümmer, B.
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(2018), Relating drug response to epigenetic and genetic markers using a region-based kernel score test, BMC Proceedings 12: 47
Yasmeen, S., Burger, P., Friedrichs, S., Papiol, S. & Bickeböller, H.
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(2018), Schätzverfahren für individuelles Preissetzungsverhalten im Lebensmitteleinzelhandel, Ph.D. thesis, Georg-August-Universität Göttingen
Schulze Bisping, C.
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(2018), Somewhere in between towns, markets, and neighbors: Agricultural transition in the rural-urban interface of Bangalore, India, courant Research Centre Poverty, Equity and Growth Discussion Papers 256: 1-20
Steinhübel, L.
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(2018), Spatial community turnover of pollinators is relaxed by semi-natural habitats, but not by mass-owering crops in agricultural landscapes, Biological Conservation 221: 59-66
Beduschi, T., Kormann, U., Tscharntke, T. & Scherber, C.
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(2018), Structural equation models for dealing with spatial confounding, The American Statistician 72: 239-252
Thaden, H. & Kneib, T.
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(2018), The effect of farm characteristics on the persistence of technical inefficiency: a case study in German dairy farming, European Review of Agricultural Economics 45: 3-25
Skevas, I., Emvalomatis, G. & Brümmer, B.
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(2018), The provision of medical services, regional diversity, and population well-being: A health frontier approach, Ph.D. thesis, Georg-August-Universität Göttingen
Schley, K.
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(2018), Understanding the economic determinants of the severity of operational losses: A regularized generalized Pareto regression approach, Journal of Applied Econometrics
Hambuckers, J., Groll, A. & Kneib, T.
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(2018),Density-dependent spatial patterning of woody plants differs between a semi-arid and a mesic savanna in South Africa, Journal of Arid Environments 157: 103-112
Hesselbarth, M.H.K., Wiegand, K., Dreber, N., Kellner, K., Esser, D.S. & Tsvuura, Z.
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(2019), A unied framework for land cover monitoring based on a discrete global sampling grid (GSG), Environmental Monitoring and Assessment 191
Fehrmann, L., Kukunda, C.B., Nölke, N., Schnell, S., Seidel, D., Magnussen, S. & Kleinn, C.
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(2019), Analyzing the relationship between historic canopy dynamics and current plant species diversity in the herb layer oftemperate forests using long-term Landsat time series, Remote Sensing of Environment 232: 111305
Graf, W., Kleinn, C., Schall, P., Nauss, T., Detsch, F. & Magdon, P.
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(2019), Bayesian effect selection in structured additive distributional regression models
Klein, N., Carlan, M., Kneib, T., Lang, S. & Wagner, H.
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(2019), Estimating value-at-risk for the g-and-h distribution: an indirect inference approach, Quantitative Finance 19: 1255-1266
Bee, M., Hambuckers, J. & Trapin, L.
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(2019), Land-sharing/-sparing connectivity landscapes for ecosystem services and biodiversity conservation, People and Nature 1: 262-272
Grass, I., [...], Librán-Embid, F., Klaus, F., Udy, K. & Tscharntke, T.
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(2019), LASSO-type penalization in the framework of generalized additive models for location, scale and shape, Computational Statistics & Data Analysis 140: 59-73
Groll, A., Hambuckers, J., Kneib, T. & Umlauf, N.
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(2019), Lost in translation: On the problem of data coding in penalized whole genome regression with interactions, G3:Genes|Genomes|Genetics
Martini, J.W.R., Rosales, F., Ha, N.T., Heise, J., Wimmer, V. & Kneib, T.
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(2019), Multivariate effect priors in bivariate semiparametric recursive gaussian models, Computational Statistics & Data Analysis 137: 51-66
Thaden, H., Klein, N. & Kneib, T.
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(2019), Polygenic risk for schizophrenia and global assessment of functioning - a comparison with in-silico data, Journal of Psychiatry and Brain Science
Yasmeen, S., Papiol, S., Falkai, P., Schulze, T.G. & Bickeböller, H.
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(2019), Provision of health care services and regional diversity in Germany: insights from a Bayesian health frontier analysis with spatial dependencies, The European Journal of Health Economics
Haschka, R.E., Schley, K. & Herwartz, H.
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(2019), Scale-guided mapping of forest stand structural heterogeneity from airborne LiDAR, Ecological Indicators 102: 410-425
Kukunda, C.B., Beckschäfer, P., Magdon, P., Schall, P., Wirth, C. & Kleinn, C.
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(2019), Urbanization, agricultural intensification, and environmental services: A spatial analysis, Ph.D. thesis, Georg-August-Universität Göttingen
Steinhübel, L.
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(2020), Noncrossing structured additive multiple-output bayesian quantile regression models, Statistics and Computing 97: 825
Santos, B. & Kneib, T.