Etablierung eines humanen ex-vivo Zellkultur-Modells aus "reprogrammierten" Fibroblasten (iPS-Zellen) von Parkinson-Patienten mit LRRK2-Muation

Applicant Dr. Martina Wölfle

Subject Area Molecular and Cellular Neurology and Neuropathology

Term from 2010 to 2013

Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 176910480

Final Report Year 2014

No abstract available

Genetic Correction of a LRRK2-Mutation in Human iPSCs Links Parkinsonian Neurodgeneration to ERK-Dependent Changes in Gene Expression. Cell Stem Cell. 2013 Mar 7;12(3):354-67
Reinhardt, Peter; Schmid, Benjamin; Burbulla, Lena F.; Schöndorf, David C.; Wagner, Lydia; Glatza, Michael; Höing, Susanne; Hargus, Gunnar; Heck, Susanna A.; Dhingra, Ashutosh; Wu, Guangming; Müller, Stephan; Brockmann, Kathrin; Kluba, Torsten; Maisel, Martina; Krüger, Rejko; Berg, Daniela; Tsytsyura, Yaroslav; Thiel, Cora S.; ... & Sterneckert, Jared

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