The identification of novel receptors involved in recognition of Mycobacterium tuberculosis

• Applicant: Dr. Georgia Schäfer, Ph.D.
• Subject Area: Parasitology and Biology of Tropical Infectious Disease Pathogens
• Term: from 2005 to 2008
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 19145300

• Final Report Year: 2008

Final Report Abstract

No abstract available

Publications

• (2002). Interaction of Early Growth Response Protein 1 (Egr-1), Specificity Protein 1 (Sp1), and Cyclic Adenosine 3'5-Monophospohate Response Element Binding Protein (CREB) at a proximal response element is critical for gastrin-dependent activation of the chromogranin A promoter. Mol Endocrin 16(2): 2802-2818
  Raychowdhury R, Schäfer G, Fleming J, Rosewicz S, Wiedenmann B, Wang TC and Höcker M
  
• (2003). Effects of interferon alpha on vascular endothelial growth factor gene transcription and tumor angiogenesis. J Natl Cancer Inst 95(6):437-448
  Von Marschall Z, Scholz A, Cramer T, Schäfer G, Schirner M, Oberg K, Wiedenmann B, Höcker M, Rosewicz S
  
• (2003). Oxidative Stress Regulates Vascular Endothelial Growth Factor-A Gene Transcription through Sp1- and Sp3-dependent Activation of Two Proximal GC-rich Promoter Elements. J Biol Chem 278(10): 8190-8198
  Schäfer G, Cramer T, Suske G, Schlag PM, Kemmner W, Wiedenmann B and Höcker M
  
• (2003). Transforming growth factor beta 1 stimulates vascular endothelial growth factor gene transcription in human cholangiocellular carcinoma cells. Cancer Res 63(5):1083-1092
  Benckert C, Jonas S, Cramer T, Von Marschall Z, Schäfer G, Peters M, Wagner K, Radke C, Wiedenmann B, Neuhaus P, Höcker M, Rosewicz S
  
• (2004). Helicobacter pylori stimulates host vascular endothelial growth factor-A (vegf-A) gene expression via MEK/ERK-dependent activation of Sp1 and Sp3. FASEB J 18(1): 218-220
  Strowski MZ, Cramer T, Schäfer G, Jüttner S, Walduck A, Schipani E, Kemmner W, Wessler S, Wunder C, Weber M, Meyer TF, Wiedenmann B, Jons T, Naumann M, Höcker M
  
• (2005). The Saccharomyces cerevisiae linker histone Hho1p, with two globular domains, can simultaneously bind to two four-way junction DNA molecules. Biochemistry 44: 16766-16775
  Schäfer G, Smith EM, Patterton HG
  
• (2008). Regulation of Vascular Endothelial Growth Factor D by Orphan Receptors Hepatocyte Nuclear Factor-4α and Chicken Ovalbumin Upstream Promoter Transcription Factors 1 and 2. Cancer Res 68(2): 457-466
  Schäfer G, Wissmann C, Hertel J, Lunyak V, Höcker M