Transcription in E. coli: Structural Basis of Nus-Factor Dependent Regulation

• Antragsteller: Professor Dr. Paul Rösch
• Fachliche Zuordnung: Strukturbiologie
• Förderung: Förderung von 2011 bis 2014
• Projektkennung: Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 192440363

• Erstellungsjahr: 2015

Keine Zusammenfassung vorhanden

Projektbezogene Publikationen (Auswahl)

• Domain interactions of the transcription-translation coupling factor Escherichia coli NusG are intermolecular and transient. Biochem J. 2011 435:783-9
  Burmann BM, Scheckenhofer U, Schweimer K, Rösch P
  
• NusA interaction with the α subunit of E. coli RNA polymerase is via the UP element site and releases autoinhibition. Structure. 2011 19:945-54
  Schweimer K, Prasch S, Sujatha PS, Bubunenko M, Gottesman ME, Rösch P
  
• The role of E. coli Nus-factors in transcription regulation and transcription:translation coupling: from structure to mechanism. Transcription. 2011 2:130-4
  Burmann BM, Rösch P
  
• An α-helix to β-barrel domain switch transforms the transcription factor RfaH into a translation factor. Cell. 2012 150:291-303
  Burmann, Björn M.; Knauer, Stefan H.; Sevostyanova, Anastasia; Schweimer, Kristian; Mooney, Rachel A.; Landick, Robert; Artsimovitch, Irina & Rösch, Paul
  
• Fast mapping of biomolecular interfaces by Random Spin Labeling (RSL). J Biomol Struct Dyn. 2012 29:793-8
  Hartl, Maximilian J.; Burmann, Björn M.; Prasch, Stefan J.; Schwarzinger, Clemens; Schweimer, Kristian; Wöhrl, Birgitta M.; Rösch, Paul & Schwarzinger, Stephan
  
• Transformation: the next level of regulation. RNA Biol. 2012A 9:1418-23
  Knauer, Stefan H.; Rösch, Paul & Artsimovitch, Irina
  
• Transformer proteins. Cell Cycle. 2012B 11:4289- 90
  Knauer SH, Artsimovitch I, Rösch P
  
• An autoinhibited state in the structure of Thermotoga maritima NusG. Structure. 2013 21:365-75
  Drögemüller, Johanna; Stegmann, Christian M.; Mandal, Angshuman; Steiner, Thomas; Burmann, Björn M.; Gottesman, Max E.; Wöhrl, Birgitta M.; Rösch, Paul; Wahl, Markus C. & Schweimer, Kristian
  
• Interdomain contacts control folding of transcription factor RfaH. Nucleic Acids Res. 2014 41:10077-85
  Tomar, Sushil Kumar; Knauer, Stefan H.; NandyMazumdar, Monali; Rösch, Paul & Artsimovitch, Irina
  
• Transformers - the science, not the fiction. QUIPS article of the Protein Data Bank in Europe. 2013 06/2013
  Knauer SH
  
• Determination of RNA polymerase binding surfaces o transcription factors by NMR spectroscopy. Scientific Reports volume 5, Article number: 16428 (2015)
  Drögemüller, Johanna; Strauß, Martin; Schweimer, Kristian; Jurk, Marcel; Rösch, Paul & Knauer, Stefan H.
  
• Exploring RNA Polymerase Regulation by NMR Spectroscopy, Sci Rep. Scientific Reports volume 5, Article number: 10825 (2015)
  Drögemüller, Johanna; Strauß, Martin; Schweimer, Kristian; Wöhrl, Birgitta M.; Knauer, Stefan H. & Rösch, Paul
  
• The two domains of Mycobacterium tuberculosis NusG protein are dynamically independent. J Biomol Dyn. Journal of Biomolecular Structure and Dynamics, 34:2, 352-361, 2016
  Strauß, Martin; Schweimer, Kristian; Burmann, Björn M.; Richter, Anne; Güttler, Stephanie; Wöhrl, Birgitta M. & Rösch, Paul