The roles of THOC 5/Fms interacting protein, a member of mRNA export complex THOC, in the immediate-early gene expression induced by a cell differentiation signal.

• Applicant: Professorin Dr. Teruko Tamura-Niemann (†)
• Subject Area: Cell Biology
• Term: from 2012 to 2020
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 217461545

• Final Report Year: 2020

No abstract available

Publications

• (2016) Targeting multiple signaling pathways: Depletion of three combined THOC5, mRNA export protein, target genes synergistically induces human hepatocellular carcinoma cell death. Oncogene, 35, 3872- 2879
  Saran, S.; Tran, D. D. H.; Ewald, F.; Koch, A.; Hoffmann, A.; Koch, M.; Nashan, B. & Tamura, T.
  
• (2016). mRNA export protein THOC5 as a tool for identification of target genes for cancer therapy. Cancer letters, 373, 222-226
  Tran, Doan Duy Hai; Saran, Shashank; Koch, Alexandra & Tamura, Teruko
  
• (2018) Myc target gene, long intergenic noncoding RNA, Linc00176 in hepatocellular carcinoma regulates cell cycle and cell survival by titrating tumor suppressor microRNAs. Oncogene, 37, 75-85
  Tran, D. D. H.; Kessler, C.; Niehus, S. E.; Mahnkopf, M.; Koch, A. & Tamura, T.
  
• (2019) Myc/Max dependent intronic long antisense noncoding RNA, EVA1A-AS, suppresses the expression of Myc/Max dependent anti-proliferating gene EVA1A in a U2 dependent manner. Sci Rep;9(1):17319
  Niehus, Svenja E.; Allister, Aldrige B.; Hoffmann, Andrea; Wiehlmann, Lutz; Tamura, Teruko & Tran, Doan Duy Hai