Spatio-temporal control over cell and membrane functions with light-driven nanoagents (B09)

• Subject Area: Biochemistry
• Term: from 2012 to 2024
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 201269156

B09 develops photoresponsive reagents to control cellular and biophysical processes with the spatiotemporal resolution of light, for a better understanding of cell biology and mechanics. B09 will continue to develop photoswitchable cytoskeleton modulators for animal studies and for subcellular resolution, and will further explore photoresponsive membrane modulators with novel molecular switches. We also develop photoresponsive gel crosslinkers that together with many SFB1032 groups will be used as light-controlled tools to study cell migration; and we work towards subcellular relocalisation reagents to study signaling and protein-protein interactions.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1032: Nanoagents for Spatio-temporal Control of Molecular and Cellular Reactions
• Applicant Institution: Ludwig-Maximilians-Universität München
• Project Head: Dr. Oliver Thorn-Seshold, since 3/2017