The role of nicotinamide phosphoribosyltransferase (NAMPT) for oncogenic MYC functions and tumor-stroma crosstalk

• Applicant: Dr. Antje Menssen
• Subject Area: Pathology
• Term: from 2013 to 2017
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 233753500

• Final Report Year: 2019

No abstract available

Publications

• AP4 is a mediator of epithelial-mesenchymal transition and metastasis in colorectal cancer. J Exp Med. 2013 Jul 1;210(7):1331-50
  Jackstadt, Rene; Röh, Simone; Neumann, Jens; Jung, Peter; Hoffmann, Reinhard; Horst, David; Berens, Christian; Bornkamm, Georg W.; Kirchner, Thomas; Menssen, Antje & Hermeking, Heiko
  
• c-MYC-mediated regulations in colorectal cancer. (summary of habilitation) Pathologe. 2013 Nov;34 Suppl 2:274-6
  Menssen, A.
  
• Genome-wide analysis of c-MYC-regulated mRNAs and miRNAs, and c-MYC DNA binding by next-generation sequencing. Methods Mol Biol. 2013;1012:145-85
  Jackstadt, Rene; Menssen, Antje & Hermeking, Heiko
  
• Expression of n-MYC, NAMPT and SIRT1 in Basal Cell Carcinomas and their Cells of Origin. Acta Derm Venereol. 2018 Dec 27;99(1):63-71
  Brandl, L.; Hartmann, D.; Kirchner, T. & Menssen, A.
  
• The c-MYC/NAMPT/SIRT1 feedback loop is activated in early classical and serrated route colorectal cancer and represents a therapeutic target. Med Oncol. 2018 Nov 20;36(1):5
  Brandl, Lydia; Kirstein, Nina; Neumann, Jens; Sendelhofert, Andrea; Vieth, Michael; Kirchner, Thomas & Menssen, Antje