The role of nicotinamide phosphoribosyltransferase (NAMPT) for oncogenic MYC functions and tumor-stroma crosstalk

• Applicant: Dr. Antje Menssen
• Subject Area: Pathology
• Term: from 2013 to 2017
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 233753500

• Final Report Year: 2019

Final Report Abstract

No abstract available

Publications

• AP4 is a mediator of epithelial-mesenchymal transition and metastasis in colorectal cancer. J Exp Med. 2013 Jul 1;210(7):1331-50
  Jackstadt R, Röh S, Neumann J, Jung P, Hoffmann R, Horst D, Berens C, Bornkamm GW, Kirchner T, Menssen A, Hermeking H
  (See online at https://doi.org/10.1084/jem.20120812)
• c-MYC-mediated regulations in colorectal cancer. (summary of habilitation) Pathologe. 2013 Nov;34 Suppl 2:274-6
  Menssen A
  (See online at https://doi.org/10.1007/s00292-013-1819-5)
• Genome-wide analysis of c-MYC-regulated mRNAs and miRNAs, and c-MYC DNA binding by next-generation sequencing. Methods Mol Biol. 2013;1012:145-85
  Jackstadt R, Menssen A, Hermeking H
  (See online at https://doi.org/10.1007/978-1-62703-429-6_11)
• Expression of n-MYC, NAMPT and SIRT1 in Basal Cell Carcinomas and their Cells of Origin. Acta Derm Venereol. 2018 Dec 27;99(1):63-71
  Brandl L, Hartmann D, Kirchner T, Menssen A
  (See online at https://doi.org/10.2340/00015555-3031)
• The c-MYC/NAMPT/SIRT1 feedback loop is activated in early classical and serrated route colorectal cancer and represents a therapeutic target. Med Oncol. 2018 Nov 20;36(1):5
  Brandl L, Kirstein N, Neumann J, Sendelhofert A, Vieth M, Kirchner T, Menssen A
  (See online at https://doi.org/10.1007/s12032-018-1225-1)