Bilateral decision networks for eye and arm movements

• Antragsteller: Dr. Igor Kagan
• Fachliche Zuordnung: Kognitive, systemische und Verhaltensneurobiologie
• Förderung: Förderung von 2013 bis 2017
• Projektkennung: Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 211740722

Igor Kagan and Melanie Wilke will investigate the role of intra- and inter-hemispheric interactions in the parietal areas LIP and PRR for decision-making related to eye and arm movements. By performing bi-hemispheric simultaneous recordings from these areas, in combination with unilateral reversible inactivation, this group will investigate how this bilateral neuronal network processes visual information to arrive at decisions related to the planning of saccadic eye and arm reaching movements, and how neuronal perturbations in the lesioned hemisphere affect the activity in the intact hemisphere. Spiking and local field potential (LFP) activity from these experiments will then be compared to concurrent primate fMRI experiments that will employ a similar design. These experiments will shed new light on how specific neuronal substrates from both hemispheres compete and collaborate for arriving at decisions for actions, and how the impaired inter-hemispheric balance causes inactivation-induced deficits.

• DFG-Verfahren: Forschungsgruppen
• Teilprojekt zu: FOR 1847: Physiologische Grundlagen verteilter Informationsverarbeitung als Grundlage höherer Hirnleistungen nicht humaner Primaten
• Großgeräte: Upgrade data acquisition system
• Gerätegruppe: 3440 Elektrophysiologische Meßsysteme (außer 300-309 und 340-343)
• Beteiligte Person: Professorin Dr. Melanie Wilke