Glycosaminoglycan-poly (ethylene glycol) hydrogels for improving dermal wound healing (A10)

• Subject Area: Biomaterials ; Dermatology
• Term: from 2013 to 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 59307082

C. Werner and U. Freudenberg develop multi-phased hydrogel materials, to combine presentation and sequestration of key signaling molecules of wound healing. At the same time the auto regulative release of bioactive substances from GAG-based polymer networks and the functionalization of the hydrogels with antiseptic and anti-oxidative substances are to be developed. The potential of these multi-phase, interactive biomaterials systems to stimulate cutaneous wound healing, bone regeneration and to modulate morphogenesis will be characterized.

• DFG Programme: CRC/Transregios
• Subproject of: TRR 67: Functional Biomaterials for Controlling Healing Processes in Bone und Skin - From Material Science to Clinical Application
• Applicant Institution: Universität Leipzig
• Project Heads: Dr.-Ing. Uwe Freudenberg; Professor Dr. Carsten Werner