GSC 97:  Dresden International Graduate School for Biomedicine and Bioengineering (DIGS-BB)

• Subject Area: Medicine
• Term: from 2006 to 2018
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 24185540

• Final Report Year: 2020

Final Report Abstract

The Dresden International Graduate School for Biomedicine and Bioengineering (DIGS-BB), founded in 2006, currently hosts 112 PhD students and 72 Research groups. Together with its partner program, the International Max Planck Research School for Cell, Developmental and Systems Biology (IMPRS- CellDevoSys) it has become one of the largest international PhD programs in the field of life sciences in Germany. As an innovative cross-faculty institution of the TU Dresden it serves as a model for the university- wide doctoral system. Approximately 700 junior scientists from all over the world apply each year for admission to one of its six highly interconnected scientific research tracks “Cell, Molecular and Developmental Biology”, “Biomedicine”, “Regenerative and Degenerative Biology”, “Bioengineering and Biomaterials”, “Biophysics” and “Computational Biology”. By educating and supporting the selected young scientists, the DIGS-BB is key for the high standards and extraordinary dynamics that drive the life sciences at TUD. The factors that ensure the quality of DIGS-BB PhD students are (i) the highly competitive selection process of the applicants; (ii) a supervision concept that is tailored for each doctoral candidate individually; (iii) a support structure that offers state-of-the art technologies including experts in the fields; and (iv) a training concept that has been adapted to reflect the interdisciplinary orientation of the research projects. Thanks to the support gained through the privileged recruitment of excellent doctoral candidates and the anchoring and integration in the strong interdisciplinary community of Biopolis Dresden, the DIGS-BB is also an excellent career-advancing institution for junior research group leaders and postdocs. In the second funding period, the DIGS-BB extended the support and supervision aspects to the postdoctoral phase, as well as to BSc and Master students via DIGS-BB research internship programs. Also, PhD students profited from opportunities offered to outreach their research data, as well as to receive career advice along the PhD time. Furthermore, junior group leaders have been supported by the status of “TUD Young Investigators” that allows this high-performing group the supervision of PhD students, participation in doctorate proceedings as reviewers and examiners and integration in the respective Faculties. By pursuing the successful path run since its foundation in 2006 and by continually improving its offers, the DIGS- BB has successfully established itself as an internationally recognized and leading graduate center.

Link to the final report

https://doi.org/10.2314/KXP:1699289700

Publications

• Acute inflammation initiates the regenerative response in the adult zebrafish brain. Science. 2012 Dec 7;338(6112):1353-6
  Kyritsis N, Kizil C, Zocher S, Kroehne V, Kaslin J, Freudenreich D, Iltzsche A, Brand M
  
• Combined RNAi and localization for functionally dissecting long noncoding RNAs. Nat Methods. 2012 Feb 12;9(4):360-2
  Chakraborty D, Kappei D, Theis M, Nitzsche A, Ding L, Paszkowski-Rogacz M, Surendranath V, Berger N, Schulz H, Saar K, Hubner N, Buchholz F
  
• Elastic volume reconstruction from series of ultra-thin microscopy sections. Nat Methods. 2012 Jun 10;9(7):717-20
  Saalfeld S, Fetter R, Cardona A, Tomancak P
  
• Fiji: an open-source platform for biological-image analysis. Nat Methods. 2012 Jun 28;9(7):676-82
  Schindelin J, Arganda-Carreras I, Frise E, Kaynig V, Longair M, Pietzsch T, Preibisch S, Rueden C, Saalfeld S, Schmid B, Tinevez JY, White DJ, Hartenstein V, Eliceiri K, Tomancak P, Cardona A
  
• Forces driving epithelial spreading in zebrafish gastrulation. Science. 2012 Oct 12;338(6104):257- 60
  Behrndt M, Salbreux G, Campinho P, Hauschild R, Oswald F, Roensch J, Grill SW, Heisenberg CP
  
• Meiotic prophase requires proteolysis of M phase regulators mediated by the meiosis-specific APC/CAma1. Cell. 2012 Oct 26;151(3):603-18
  Okaz E, Argüello-Miranda O, Bogdanova A, Vinod PK, Lipp JJ, Markova Z, Zagoriy I, Novak B, Zachariae W
  
• Omnidirectional microscopy. Nat Methods. 2012 Jun 28;9(7):656-7
  Weber M, Huisken J
  
• Synthetic Bio-nanoreactor: Mechanical and Chemical Control of Polymersome Membrane Permeability. Angew Chem Int Ed Engl. 2012 Apr 27;51(18):4448-51
  Gaitzsch J, Appelhans D, Wang L, Battaglia G, Voit B
  
• A genomic toolkit to investigate kinesin and myosin motor function in cells. Nat Cell Biol. 2013 Mar;15(3):325-34
  Maliga Z, Junqueira M, Toyoda Y, Ettinger A, Mora-Bermúdez F, Klemm RW, Vasilj A, Guhr E, Ibarlucea-Benitez I, Poser I, Bonifacio E, Huttner WB, Shevchenko A, Hyman AA
  
• ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing. Genes Dev. 2013 Jul 1;27(13):1484-94
  Royo H, Prosser H, Ruzankina Y, Mahadevaiah SK, Cloutier JM, Baumann M, Fukuda T, Höög C, Tóth A, de Rooij DG, Bradley A, Brown EJ, Turner JM
  
• Defined Polymer-Peptide Conjugates to Form Cell-Instructive starPEG-Heparin Matrices In Situ. Adv Mater. 2013 May 14;25(18):2606-10
  Tsurkan MV, Chwalek K, Prokoph S, Zieris A, Levental KR, Freudenberg U, Werner C
  
• Dynamic Guiding of Motor-Driven Microtubules on Electrically Heated, Smart Polymer Tracks. Nano Lett. 2013 Jun 10
  Schroeder V, Korten T, Linke H, Diez S, Maximov I
  
• Dynein motion switches from diffusive to directed upon cortical anchoring. Cell. 2013 Jun 20;153(7):1526-36
  Ananthanarayanan V, Schattat M, Vogel SK, Krull A, Pavin N, Tolić-Nørrelykke IM
  
• Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape. Nat Biotechnol. 2013 Jul;31(7):638-46
  Gilleron J, Querbes W, Zeigerer A, Borodovsky A, Marsico G, Schubert U, Manygoats K, Seifert S, Andree C, Stöter M, Epstein-Barash H, Zhang L, Koteliansky V, Fitzgerald K, Fava E, Bickle M, Kalaidzidis Y, Akinc A, Maier M, Zerial M
  
• Integration of chemical and RNAi multiparametric profiles identifies triggers of intracellular mycobacterial killing. Cell Host Microbe. 2013 Feb 13;13(2):129-42
  Sundaramurthy V, Barsacchi R, Samusik N, Marsico G, Gilleron J, Kalaidzidis I, Meyenhofer F, Bickle M, Kalaidzidis Y, Zerial M
  
• Lypd6 enhances Wnt/β-catenin signaling by promoting Lrp6 phosphorylation in raft plasma membrane domains. Dev Cell. 2013 Aug 26;26(4):331-45
  Özhan G, Sezgin E, Wehner D, Pfister AS, Kühl SJ, Kagermeier-Schenk B, Kühl M, Schwille P, Weidinger G
  
• Lypd6 enhances Wnt/β-catenin signaling by promoting Lrp6 phosphorylation in raft plasma membrane domains. Dev Cell. 2013 Aug 26;26(4):331-45
  Özhan G, Sezgin E, Wehner D, Pfister AS, Kühl SJ, Kagermeier-Schenk B, Kühl M, Schwille P, Weidinger G
  
• Neuroinflammation and central nervous system regeneration in vertebrates. Trends Cell Biol. 2013 Sep 9. Review. doi:pii: S0962-8924(13)00137-2
  Kyritsis N, Kizil C, Brand M
  
• OpenSPIM: an open-access light-sheet microscopy platform. Nat Methods. 2013 Jul;10(7):598-9
  Pitrone PG, Schindelin J, Stuyvenberg L, Preibisch S, Weber M, Eliceiri KW, Huisken J, Tomancak P
  
• Pivoting of microtubules around the spindle pole accelerates kinetochore capture. Nat Cell Biol. 2013 Jan;15(1):82-7
  Kalinina I, Nandi A, Delivani P, Chacón MR, Klemm AH, Ramunno-Johnson D, Krull A, Lindner B, Pavin N, Tolić-Nørrelykke IM
  
• Progenitor networking in the fetal primate neocortex. Neuron. 2013 Oct 16;80(2):259-62
  Huttner WB, Kelava I, Lewitus E
  
• Quantitative interaction screen of telomeric repeat-containing RNA reveals novel TERRA regulators. Genome Res. 2013 Oct 22
  Scheibe M, Arnoult N, Kappei D, Buchholz F, Decottignies A, Butter F, Mann M
  
• Reactivating head regrowth in a regeneration-deficient planarian species. Nature. 2013 Aug 1;500(7460):81-4
  Liu SY, Selck C, Friedrich B, Lutz R, Vila-Farré M, Dahl A, Brandl H, Lakshmanaperumal N, Henry I, Rink JC
  
• Secretion and signaling activities of lipoprotein-associated hedgehog and non-sterol-modified hedgehog in flies and mammals. PLoS Biol. 2013 Mar;11(3):e1001505
  Palm W, Swierczynska MM, Kumari V, Ehrhart-Bornstein M, Bornstein SR, Eaton S
  
• The helicase-like domains of type III restriction enzymes trigger long-range diffusion along DNA. Science. 2013 Apr 19;340(6130):353-6
  Schwarz FW, Tóth J, van Aelst K, Cui G, Clausing S, Szczelkun MD, Seidel R
  
• Tightly anchored tissue-mimetic matrices as instructive stem cell microenvironments. Nat Methods. 2013 Aug;10(8):788-9
  Prewitz MC, Seib FP, von Bonin M, Friedrichs J, Stißel A, Niehage C, Müller K, Anastassiadis K, Waskow C, Hoflack B, Bornhäuser M, Werner C
  
• A wax ester promotes collective host finding in the nematode Pristionchus pacificus. Nat Chem Biol. 2014 Apr;10(4):281-5
  Penkov S, Ogawa A, Schmidt U, Tate D, Zagoriy V, Boland S, Gruner M, Vorkel D, Verbavatz JM, Sommer RJ, Knölker HJ, Kurzchalia TV
  
• An adaptive threshold in mammalian neocortical evolution. PLoS Biol. 2014 Nov 18;12(11):e1002000
  Lewitus E, Kelava I, Kalinka AT, Tomancak P, Huttner WB
  
• Dual role of B7 costimulation in obesity-related nonalcoholic steatohepatitis and metabolic dysregulation. Hepatology. 2014 Oct;60(4):1196-210
  Chatzigeorgiou A, Chung KJ, Garcia-Martin R, Alexaki VI, Klotzsche-von Ameln A, Phieler J, Sprott D, Kanczkowski W, Tzanavari T, Bdeir M, Bergmann S, Cartellieri M, Bachmann M, Nikolakopoulou P, Androutsellis-Theotokis A, Siegert G, Bornstein SR, Muders MH, Boon L, Karalis KP, Lutgens E, Chavakis T
  
• Fusion of protein aggregates facilitates asymmetric damage segregation. PLoS Biol. 2014 Jun 17;12(6):e1001886
  Coelho M, Lade SJ, Alberti S, Gross T, Tolić IM
  
• Genome-wide RNA Tomography in the zebrafish embryo.Cell. 2014 Oct 23;159(3):662-75
  Junker JP, Noël ES, Guryev V, Peterson KA, Shah G, Huisken J, McMahon AP, Berezikov E, Bakkers J, van Oudenaarden A
  
• High-resolution reconstruction of the beating zebrafish heart. Nat Methods. 2014 Sep;11(9):919-22
  Mickoleit M, Schmid B, Weber M, Fahrbach FO, Hombach S, Reischauer S, Huisken J
  
• Kit regulates HSC engraftment across the human-mouse species barrier. Cell. 2014 Aug 7;15(2):227-38
  Cosgun KN, Rahmig S, Mende N, Reinke S, Hauber I, Schäfer C, Petzold A, Weisbach H, Heidkamp G, Purbojo A, Cesnjevar R, Platz A, Bornhäuser M, Schmitz M, Dudziak D, Hauber J, Kirberg J, Waskow C
  
• Microinjection of membrane-impermeable molecules into single neural stem cells in brain tissue. Nat Protoc. 2014 May;9(5):1170-82
  Wong FK, Haffner C, Huttner WB, Taverna E
  
• Production of systemically circulating Hedgehog by the intestine couples nutrition to growth and development. Genes Dev. 2014 Dec 1;28(23):2636-51
  Rodenfels J, Lavrynenko O, Ayciriex S, Sampaio JL, Carvalho M, Shevchenko A, Eaton S
  
• Shape-controlled synthesis of gold nanostructures using DNA origami molds. Nano Lett. 2014 Nov 12;14(11):6693-8
  Helmi S, Ziegler C, Kauert DJ, Seidel R
  
• Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms. Immunity. 2014 Apr 17;40(4):477- 89
  Xiao S, Yosef N, Yang J, Wang Y, Zhou L, Zhu C, Wu C, Baloglu E, Schmidt D, Ramesh R, Lobera M, Sundrud MS, Tsai PY, Xiang Z, Wang J, Xu Y, Lin X, Kretschmer K, Rahl PB, Young RA, Zhong Z, Hafler DA, Regev A, Ghosh S, Marson A, Kuchroo VK
  
• The Coilin Interactome Identifies Hundreds of Small Noncoding RNAs that Traffic through Cajal Bodies. Mol Cell. 2014 Nov 6;56(3):389-99
  Machyna M, Kehr S, Straube K, Kappei D, Buchholz F, Butter F, Ule J, Hertel J, Stadler PF, Neugebauer KM
  
• Tissue-engineered 3D tumor angiogenesis models: Potential technologies for anti-cancer drug discovery. Adv Drug Deliv Rev. 2014 Dec 15;79-80C:30-39
  Chwalek K, Bray LJ, Werner C
  
• Using pancreas tissue slices for in situ studies of islet of Langerhans and acinar cell biology. Nat Protoc. 2014 Dec;9(12):2809-22
  Marciniak A, Cohrs CM, Tsata V, Chouinard JA, Selck C, Stertmann J, Reichelt S, Rose T, Ehehalt F, Weitz J, Solimena M, Slak Rupnik M, Speier S
  
• A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances. Cell. 2015 Oct 22;163(3):712-23
  Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M
  
• A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation. Cell. 2015 Aug 27;162(5):1066-77
  Patel A, Lee HO, Jawerth L, Maharana S, Jahnel M, Hein MY, Stoynov S, Mahamid J, Saha S, Franzmann TM, Pozniakovski A, Poser I, Maghelli N, Royer LA, Weigert M, Myers EW, Grill S, Drechsel D, Hyman AA, Alberti S
  
• A Single-Strand Annealing Protein Clamps DNA to Detect and Secure Homology. PLoS Biol. 2015 Aug 13;13(8):e1002213
  Ander M, Subramaniam S, Fahmy K, Stewart AF, Schäffer E
  
• Diffusible crosslinkers generate directed forces in microtubule networks. Cell. 2015 Mar 12;160(6):1159-68
  Lansky Z, Braun M, Lüdecke A, Schlierf M, ten Wolde PR, Janson ME, Diez S
  
• Effects of high-dose oral insulin on immune responses in children at high risk for type 1 diabetes: the Pre-POINT randomized clinical trial. JAMA. 2015 Apr 21;313(15):1541-9
  Bonifacio E, Ziegler AG, Klingensmith G, Schober E, Bingley PJ, Rottenkolber M, Theil A, Eugster A, Puff R, Peplow C, Buettner F, Lange K, Hasford J, Achenbach P; Pre-POINT Study Group
  
• Engineering Functional Polymer Capsules toward Smart Nanoreactors. Chem Rev. 2015 Aug 31
  Gaitzsch J, Huang X, Voit B
  
• Long non-coding RNAs in corticogenesis: deciphering the non-coding code of the brain. EMBO J. 2015 Oct 29
  Aprea J, Calegari F
  
• Quantifying the density and utilization of active sites in non-precious metal oxygen electroreduction catalysts. at Commun. 2015 Oct 21;6:8618
  Sahraie NR, Kramm UI, Steinberg J, Zhang Y, Thomas A, Reier T, Paraknowitsch JP, Strasser P
  
• C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility. Nat Commun. 2016 Oct 31;7:13298
  Gómez-H L, Felipe-Medina N, Sánchez-Martín M, Davies OR, Ramos I, García-Tuñón I, de Rooij DG, Dereli I, Tóth A, Barbero JL, Benavente R, Llano E, Pendas AM
  
• Corrigendum: Noncovalent Hydrogel Beads as Microcarriers for Cell Culture. Angew Chem Int Ed Engl. 2016 Aug 26;55(36):10549
  Wieduwild R, Krishnan S, Chwalek K, Boden A, Nowak M, Drechsel D, Werner C, Zhang Y
  
• Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity. Nat Biotechnol. 2016 Apr;34(4):401-9
  Karpinski J, Hauber I, Chemnitz J, Schäfer C, Paszkowski-Rogacz M, Chakraborty D, Beschorner N, Hofmann-Sieber H, Lange UC, Grundhoff A, Hackmann K, Schrock E, Abi-Ghanem J, Pisabarro MT, Surendranath V, Schambach A, Lindner C, van Lunzen J, Hauber J, Buchholz F
  
• FGF8 and SHH substitute for anterior-posterior tissue interactions to induce limb regeneration. Nature. 2016 May 19;533(7603):407-10
  Nacu E, Gromberg E, Oliveira CR, Drechsel D, Tanaka EM
  
• Identification of proliferative and mature β-cells in the islets of Langerhans. Nature. 2016 Jul 21;535(7612):430-4
  Bader E, Migliorini A, Gegg M, Moruzzi N, Gerdes J, Roscioni SS, Bakhti M, Brandl E, Irmler M, Beckers J, Aichler M, Feuchtinger A, Leitzinger C, Zischka H, Wang-Sattler R, Jastroch M, Tschöp M, Machicao F, Staiger H, Häring HU, Chmelova H, Chouinard JA, Oskolkov N, Korsgren O, Speier S, Lickert H
  
• Inactivation of Cancer Mutations Utilizing CRISPR/Cas9. Natl Cancer Inst. 2016 Aug 30;109(1). pii: djw183
  Gebler C, Lohoff T, Paszkowski-Rogacz M, Mircetic J, Chakraborty D, Camgoz A, Hamann MV, Theis M, Thiede C, Buchholz F
  
• Meiotic DNA break formation requires the unsynapsed chromosome axis-binding protein IHO1 (CCDC36) in mice. Nat Cell Biol. 2016 Nov;18(11):1208- 1220
  Stanzione M, Baumann M, Papanikos F, Dereli I, Lange J, Ramlal A, Tränkner D, Shibuya H, de Massy B, Watanabe Y, Jasin M, Keeney S, Tóth A
  
• Microtubule doublets are double-track railways for intraflagellar transport trains. Science. 2016 May 6;352(6286):721-4
  Stepanek L, Pigino G
  
• Retinal transplantation of photoreceptors results in donor-host cytoplasmic exchange. Nat Commun. 2016 Oct 4;7:13028
  Santos-Ferreira T, Llonch S, Borsch O, Postel K, Haas J, Ader M
  
• Simultaneous Single-Molecule Force and Fluorescence Sampling of DNA Nanostructure Conformations Using Magnetic Tweezers. Nano Lett. 2016 Jan 13;16(1):381-6
  Kemmerich FE, Swoboda M, Kauert DJ, Grieb MS, Hahn S, Schwarz FW, Seidel R, Schlierf M
  
• The bulk of the hematopoietic stem cell population is dispensable for murine steady-state and stress hematopoiesis. Blood. 2016 Nov 10;128(19):2285-2296
  Schoedel KB, Morcos MNF, Zerjatke T, Roeder I, Grinenko T, Voehringer D, Göthert JR, Waskow C, Roers A, Gerbaulet A
  
• A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity. Nat Immunol. 2017 Jun;18(6):654-664
  Chung KJ, Chatzigeorgiou A, Economopoulou M, Garcia-Martin R, Alexaki VI, Mitroulis I, Nati M, Gebler J, Ziemssen T, Goelz SE, Phieler J, Lim JH, Karalis KP, Papayannopoulou T, Blüher M, Hajishengallis G, Chavakis T
  
• Bottom-Up Structuring and Site-Selective Modification of Hydrogels Using a Two-Photon [2+2] Cycloaddition of Maleimide. Adv Mater. 2017 Jan;29(2)
  Jungnickel C, Tsurkan MV, Wogan K, Werner C, Schlierf M
  
• Calcium Directly Regulates Phosphatidylinositol 4,5-Bisphosphate Headgroup Conformation and Recognition. Am Chem Soc. 2017 Mar 22;139(11):4019-4024
  Bilkova E, Pleskot R, Rissanen S, Sun S, Czogalla A, Cwiklik L, Róg T, Vattulainen I, Cremer PS, Jungwirth P, Coskun Ü
  
• Changes in microtubule overlap length regulate kinesin-14-driven microtubule sliding. Nat Chem Biol. 2017 Oct 16
  Braun M, Lansky Z, Szuba A, Schwarz FW, Mitra A, Gao M, Lüdecke A, Ten Wolde PR, Diez S
  
• Development of a genetic sensor that eliminates p53 deficient cells. Nat Commun. 2017 Nov 13;8(1):1463
  Mircetic J, Dietrich A, Paszkowski- Rogacz M, Krause M, Buchholz F
  
• Different developmental histories of beta-cells generate functional and proliferative heterogeneity during islet growth. Nat Commun. 2017 Sep 22;8(1):664
  Singh SP, Janjuha S, Hartmann T, Kayisoglu Ö, Konantz J, Birke S, Murawala P, Alfar EA, Murata K, Eugster A, Tsuji N, Morrissey ER, Brand M, Ninov N
  
• Dipolar Relaxation Dynamics at the Active Site of an ATPase Regulated by Membrane Lateral Pressure. Angew Chem Int Ed Engl. 2017 Jan 24;56(5):1269-1272
  Fischermeier E, Pospíšil P, Sayed A, Hof M, Solioz M, Fahmy K
  
• Dynamic stepwise opening of integron attC DNA hairpins by SSB prevents toxicity and ensures functionality. Nucleic Acids Res. 2017 Oct 13;45(18):10555-10563
  Grieb MS, Nivina A, Cheeseman BL, Hartmann A, Mazel D, Schlierf M
  
• Forbidden Chemistry: Two-Photon Pathway in [2+2] Cycloaddition of Maleimides. J Am Chem Soc. 2017 Aug 2;139(30):10184-10187
  Tsurkan MV, Jungnickel C, Schlierf M, Werner C
  
• Glycosaminoglycan-based hydrogels capture inflammatory chemokines and rescue defective wound healing in mice. Sci Transl Med. 2017 Apr 19;9(386). pii: eaai9044
  Lohmann N, Schirmer L, Atallah P, Wandel E, Ferrer RA, Werner C, Simon JC, Franz S, Freudenberg U
  
• Highly-Efficient Guiding of Motile Microtubules on Non-Topographical Motor Patterns. Nano Lett. 2017 Sep 13;17(9):5699-5705
  Reuther C, Mittasch M, Naganathan SR, Grill SW, Diez S
  
• Machine learning meets complex networks via coalescent embedding in the hyperbolic space. Nat Commun. 2017 Nov 20;8(1):1615
  Muscoloni A, Thomas JM, Ciucci S, Bianconi G, Cannistraci CV
  
• The contribution of homology arms to nuclease-assisted genome engineering. Nucleic Acids Res. 2017 Jul 27;45(13):8105-8115
  Baker O, Tsurkan S, Fu J, Klink B, Rump A, Obst M, Kranz A, Schröck E, Anastassiadis K, Stewart AF
  
• An E2-ubiquitin thioester-driven approach to identify substrates modified with ubiquitin and ubiquitin-like molecules. Nat Commun. 2018 Nov 14;9(1):4776
  Bakos G, Yu L, Gak IA, Roumeliotis TI, Liakopoulos D, Choudhary JS, Mansfeld J
  
• ATR is a multifunctional regulator of male mouse meiosis. Nat Commun. 2018 Jul 5;9(1):2621
  Widger A, Mahadevaiah SK, Lange J, ElInati E, Zohren J, Hirota T, Pacheco S, Maldonado-Linares A, Stanzione M, Ojarikre O, Maciulyte V, de Rooij DG, Tóth A, Roig I, Keeney S, Turner JMA
  
• Author Correction: The axolotl genome and the evolution of key tissue formation regulators. Nature. 2018 Jul;559(7712):E2
  Nowoshilow S, Schloissnig S, Fei JF, Dahl A, Pang AWC, Pippel M, Winkler S, Hastie AR, Young G, Roscito JG, Falcon F, Knapp D, Powell S, Cruz A, Cao H, Habermann B, Hiller M, Tanaka EM, Myers EW
  
• Autophagy orchestrates the regulatory program of tumor-associated myeloid-derived suppressor cells. J Clin Invest. 2018 Aug 31;128(9):3840-3852
  Alissafi T, Hatzioannou A, Mintzas K, Barouni RM, Banos A, Sormendi S, Polyzos A, Xilouri M, Wielockx B, Gogas H, Verginis P
  
• Blood Sugar Regulation for Cardiovascular Health Promotion and Disease Prevention: JACC Health Promotion Series. Am Coll Cardiol. 2018 Oct 9;72(15):1829-1844
  Schwarz PEH, Timpel P, Harst L, Greaves CJ, Ali MK, Lambert J, Weber MB, Almedawar MM, Morawietz H
  
• Coacervation-Mediated Combinatorial Synthesis of Biomatrices for Stem Cell Culture and Directed Differentiation. Adv Mater. 2018 May;30(22):e1706100
  Wieduwild R, Wetzel R, Husman D, Bauer S, El-Sayed I, Duin S, Murawala P, Thomas AK, Wobus M, Bornhäuser M, Zhang Y
  
• Conditional control of fluorescent protein degradation by an auxin-dependent nanobody. Nat Commun. 2018 Aug 17;9(1):3297
  Daniel K, Icha J, Horenburg C, Müller D, Norden C, Mansfeld J
  
• DHEA inhibits acute microglia-mediated inflammation through activation of the TrkA-Akt1/2-CREB- Jmjd3 pathway. Mol Psychiatry. 2018 Jun;23(6):1410- 1420
  Alexaki VI, Fodelianaki G, Neuwirth A, Mund C, Kourgiantaki A, Ieronimaki E, Lyroni K, Troullinaki M, Fujii C, Kanczkowski W, Ziogas A, Peitzsch M, Grossklaus S, Sönnichsen B, Gravanis A, Bornstein SR, Charalampopoulos I, Tsatsanis C, Chavakis T
  
• Diffusive tail anchorage determines velocity and force produced by kinesin-14 between crosslinked microtubules. Nat Commun. 2018 Jun 7;9(1):2214
  Lüdecke A, Seidel AM, Braun M, Lansky Z, Diez S
  
• DNA-Mold Templated Assembly of Conductive Gold Nanowires. Nano Lett. 2018 Mar 14;18(3):2116-2123
  Bayrak T, Helmi S, Ye J, Kauert D, Kelling J, Schönherr T, Weichelt R, Erbe A, Seidel R
  
• In situ-forming, cell-instructive hydrogels based on glycosaminoglycans with varied sulfation patterns.. Biomaterials. 2018 Oct;181:227-239
  Atallah P, Schirmer L, Tsurkan M, Putra Limasale YD, Zimmermann R, Werner C, Freudenberg U
  
• Label-Free Detection of Microvesicles and Proteins by the Bundling of Gliding Microtubules. Nano Lett. 2018 Jan 10;18(1):117-123
  Chaudhuri S, Korten T, Korten S, Milani G, Lana T, Te Kronnie G, Diez S
  
• Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity. Cell. 2018 Jan 11;172(1-2):147-161.e12
  Mitroulis I, Ruppova K, Wang B, Chen LS, Grzybek M, Grinenko T, Eugster A, Troullinaki M, Palladini A, Kourtzelis I, Chatzigeorgiou A, Schlitzer A, Beyer M, Joosten LAB, Isermann B, Lesche M, Petzold A, Simons K, Henry I, Dahl A, Schultze JL, Wielockx B, Zamboni N, Mirtschink P, Coskun Ü, Hajishengallis G, Netea MG, Chavakis T
  
• Pharmacophore Nanoarrays on DNA Origami Substrates as a Single-Molecule Assay for Fragment- Based Drug Discovery. Angew Chem Int Ed Engl. 2018 Nov 5;57(45):14873-14877
  Kielar C, Reddavide FV, Tubbenhauer S, Cui M, Xu X, Grundmeier G, Zhang Y, Keller A
  
• Real-Time Deformability Cytometry: Label-Free Functional Characterization of Cells. Methods Mol Biol. 2018;1678:347-369
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