Processing and Function of the Gp2/3/4 Spike of the Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)

• Applicant: Privatdozent Dr. Michael Veit
• Subject Area: Veterinary Medical Science
• Term: from 2014 to 2020
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 256219832

• Final Report Year: 2020

Final Report Abstract

No abstract available

Publications

• (2014) Signal peptide cleavage from GP3 enabled by removal of adjacent glycosylation sites does not impair replication of equine arteritis virus in cell culture, but the hydrophobic C-terminus is essential. Virus Res. 183:107-11
  Matczuk AK, Veit M
  
• (2014) Membrane proteins of arterivirus particles: Structure, topology, processing and function. Virus Res. 194:16-36
  Veit M, Matczuk AK, Sinhadri BC, Krause E, Thaa B
  
• (2017) The complex co-translational processing of glycoprotein GP5 of type 1 porcine reproductive and respiratory syndrome virus. Virus Res. 240:112-120
  Thaa B, Kaufer S, Neumann SA, Peibst B, Nauwynck H, Krause E, Veit M
  
• (2018) Differences in signal peptide processing between GP3 glycoproteins of Arteriviridae. Virology. 517:69-76
  Zhang M, Veit M
  
• (2018) Glycoprotein 3 of Porcine Reproductive and Respiratory Syndrome Virus Exhibits an Unusual Hairpin-Like Membrane Topology. J Virol. 17;92(15): e00660-18
  Zhang M, Krabben L, Wang F, Veit M