Analyse der Funktion Telomer-bindender Proteine bei der Regulation von Telomerlänge und Stabilität in vivo

• Applicant: Professor Dr. Karl Lenhard Rudolph
• Subject Area: Gastroenterology
• Term: from 2006 to 2010
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 26130861

• Final Report Year: 2010

No abstract available

Publications

• Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease. Proc Nat Acad Sci 2008, 105:11299-304
  Jiang H, Schiffer E, Song Z, Wang J, Zürbig P, Thedieck K, Moes S, Saal N, Bantel H, Jantos J, Brecht M, Jenö P, Hall MN, Hager K, Manns MP, Hecker H, Ganser A, Döhner K, Bartke A, Meissner C, Mischak H, Ju Z, Rudolph KL
  
• Short Telomeres and Prognosis of Hypertension in a Chinese Population. Hypertension 2009, 53:639-45
  Yang Z, Huang X, Jiang H, Zhang Y, Liu H, Qin C, Eisner GM, Jose P, Rudolph L, Ju Z
  
• Alterations of the systemic environment are the primary cause of impaired B- and T-lymphopoiesis in telomere dysfunctional mice. BLOOD 2010, 115:1481-9
  Song Z, Wang J, Guachalla LM, Terszowskif G, Ju Z, Rudolph KL