Einsatz eines Infrarot-Quantenkaskadenlasers zur Verfolgung irreversibler Reaktionen Flavin-bindender Lichtrezeptoren und Enzyme

• Antragsteller: Professor Dr. Tilman Kottke
• Fachliche Zuordnung: Biophysik
• Förderung: Förderung von 2015 bis 2020
• Projektkennung: Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 266942153

• Erstellungsjahr: 2020

Zusammenfassung der Projektergebnisse

Keine Zusammenfassung vorhanden

Projektbezogene Publikationen (Auswahl)

• A Blue-Light Photoreceptor Mediates the Feedback Regulation of Photosynthesis. Nature, Vol. 537. 2016, pp. 563–566.
  D. Petroutsos, R. Tokutsu, S. Maruyama, S. Flori, A. Greiner, L. Magneschi, L. Cusant, T. Kottke, M. Mittag, P. Hegemann, G. Finazzi, J. Minagawa
  
• Allosteric Communication Between DNA-Binding and Light-Responsive Domains of Diatom Class I Aureochromes. Nucleic Acids Research, Vol. 44. 2016, Issue 12, pp. 5957–5970.
  A. Banerjee, E. Herman, M. Serif, M. M. Reyna, S. Hepp, R. Pokorny, P. G. Kroth, L.-O. Essen, T. Kottke
  
• Evidence for Tautomerization of Glutamine in BLUF Blue Light Receptors by Vibrational Spectroscopy and Computational Chemistry. Scientific Reports, Vol. 6. 2016, 22669.
  T. Domratcheva, E. Hartmann, I. Schlichting, T. Kottke
  
• Chromophore-Protein Interplay during the Phytochrome Photocycle Revealed by Step-Scan FTIR Spectroscopy. Journal of the American Chemical Society, Vol. 140. 2018, Issue 39, pp.12396–12404.
  J. A. Ihalainen, E. Gustavsson, L. Schroeder, S. Donnini, H. Lehtivuori, L. Isaksson, C. Thöing, V. Modi, O. Berntsson, B. Stucki-Buchli, A. Liukkonen, H. Häkkänen, E. Kalenius, S. Westenhoff, T. Kottke
  
• Photochemically Driven Biocatalysis of Halogenases for the Green Production of Chlorinated Compounds. ChemCatChem, Vol. 10. 2018, Issue 15, pp. 3336-3341.
  L. Schroeder, M. Frese, C. Müller, N. Sewald, T. Kottke
  
• Photoreceptors Take Charge: Emerging Principles for Light Sensing. Annual Review of Biophysics, Vol. 47. 2018, pp. 291-313.
  T. Kottke, A. Xie, D. S. Larsen, W. D. Hoff
  
• Single-Shot Sub-microsecond Mid-infrared Spectroscopy on Protein Reactions with Quantum Cascade Laser Frequency Combs. Analytical Chemistry, Vol. 90. 2018, Issue 17, pp. 10494–10500.
  J. L. Klocke, M. Mangold, P. Allmendinger, A. Hugi, M. Geiser, P. Jouy, J. Faist, T. Kottke
  
• Arguments for an Additional Long-lived Intermediate in the Photocycle of the Full-length Aureochrome 1c Receptor: a Time-resolved Small-angle X-ray Scattering Study. Structural Dynamics, Vol. 6. 2019, 034701.
  S. Bannister, E. Böhm, T. Zinn, T. Hellweg, T. Kottke
  
• Swelling Behaviour of Core‐Shell Microgels in H2O, Analysed by Temperature‐Dependent FTIR Spectroscopy. Physical Chemistry Chemical Physics, Vol. 21. 2019, Issue 2, pp. 572-580.
  L. Wiehemeier, M. Cors, O. Wrede, J. Oberdisse, T. Hellweg, T. Kottke
  
• Time-resolved Infrared and Visible Spectroscopy on Cryptochrome aCRY: Basis for Red Light Reception. Biophysical Journal, Vol. 117. 2019, Issue 3, pp. 490-499.
  S. Oldemeyer, M. Mittag, T. Kottke