Neue Strategie für die Immuntherapie von Krebs mittels adenoviraler Vektoren

• Applicant: Dr. Reinhard Wähler
• Subject Area: Reproductive Medicine, Urology
• Term: from 2006 to 2009
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 27296517

• Final Report Year: 2008

Final Report Abstract

No abstract available

Publications

• Gene transfer to carcinoma of the breast with fiber-modified adenoviral vectors in a tissue slice model system. Cancer Biol Ther. 2005 Nov;4(11):1203-10
  Stoff-Khalili MA, Stoff A, Rivera AA, Mathis JM, Everts M, Wang M, Kawakami Y, Waehler R, Mathews QL, Yamamoto M, Rocconi RP, Siegal GP, Richter DF, Dall P, Zhu ZB, Curiel DT
  
• Genetic incorporation of a herpes simplex virus type 1 thymidine kinase and firefly luciferase fusion into the adenovirus protein IX for functional display on the virion. Mol Imaging. 2006 Oct-Dec;5(4):510-9
  Matthews QL, Sibley DA, Wu H, Li J, Stoff-Khalili MA, Waehler R, Mathis JM, Curiel DT
  
• Engineering targeted viral vectors for gene therapy. Nat Rev Genet. 2007 Aug;8(8):573-87
  Waehler R, Russell SJ, Curiel DT
  
• Genetic Immunotherapy of solid tumors (Genetische Immuntherapie solider Tumoren). Biospektrum 2007 Jan: 40-2
  Waehler R, Ittrich H, Müller L, Forster H, Schnieders F
  
• Optimization of capsid-incorporated antigens for an improved adenovirus vaccine approach. 10th Annual Meeting of the American Society of Gene Therapy (ASGT), May 30 - June 3, 2007, Seattle, USA
  Qiana L. Matthews, PingAr Yang, Qi Wu, Natalya Belousova, Angel A. Rivera, Marlam A. Stoff-Khalili, Reinhard Waehler, Hui-Chen Hsu, John Mountz, Hongju Wu and David T. Curiel
  
• Optimization of capsid-incorporated antigens for a novel adenovirus vaccine approach. Virol J. 2008 Aug 21;5:98
  Matthews QL, Yang P, Wu Q, Belousova N, Rivera AA, Stoff-Khalili MA, Waehler R, Hsu HC, Li Z, Li J, Mountz JD, Wu H, Curiel DT
  
• Trends in immunoconjugate and ligand-receptor based targeting development for cancer therapy. Expert Opin Drug Deliv. 2008 Jan;5(1):87-103
  Brumlik MJ, Daniel BJ, Waehler R, Curiel DT, Giles FJ, Curiel TJ