Rapid evolution of gene regulation

• Applicant: Professor Dr. John Parsch
• Subject Area: Evolution, Anthropology ; Bioinformatics and Theoretical Biology
• Term: from 2015 to 2023
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 274388701

Alterations in environmental conditions can lead to rapid, adaptive changes in gene expression. This project aims to understand cis-regulatory evolution in natural populations of the fruit fly Drosophila melanogaster. Using high-throughput RNA sequencing (RNA-seq) and reporter gene experiments, we will identify genetic variants that influence gene expression. Furthermore, we will determine the magnitude of their effect on gene expression and investigate their population dynamics.

• DFG Programme: Priority Programmes
• Subproject of: SPP 1819: Rapid evolutionary adaptation: Potential and constraints