FOR 2407:  Exploring Articular Cartilage and Subchondral Bone Degeneration and Regeneration in Osteoarthritis (ExCarBon)

• Subject Area: Medicine
• Term: since 2016
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 277277765

No abstract available

• DFG Programme: Research Units
• International Connection: United Arab Emirates

Projects

• Cellular and molecular context of cartilage adjacent subchondral bone (CASB) microstructure (Applicant Schilling, Arndt Friedrich )
• Coordination Funds (Applicant Grässel, Susanne )
• Integrins in osteoarthritis and cartilage repair (Applicants Aszódi, Attila ;  Clausen-Schaumann, Hauke )
• Interaction of heparan sulfate and integrin signaling in maintaining the articular cartilage (Applicant Vortkamp, Andrea )
• Mechanoregulated microRNAs in cartilage function and pathophysiology of osteoarthritis (Applicant Diederichs, Solvig )
• Modulation of inflammatory processes as treatment strategy in osteoarthritis (Applicant Moradi, Babak )
• Preconditioning of mesenchymal stem cells with mechanobiological load and hypoxia for joint regeneration in moderate osteoarthritis (Applicant Angele, Peter )
• Role of the sensory nervous system in subchondral bone remodeling and synovial inflammation in OA pathology (Applicant Grässel, Susanne )
• Sympathetic influences on articular cartilage regeneration capacity and osteoarthritis manifestation (Applicant Jenei-Lanzl, Zsuzsa )

• Spokesperson: Professorin Dr. Susanne Grässel