Plasticity and dynamic interactions of chitin-induced receptor-mediated innate immunity (B08)

• Subject Area: Biophysics
• Term: from 2015 to 2020
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 258780946

Plant pattern recognition receptors (PRRs), including the Arabidopsis chitin receptors CERK1 and LYK5, are the primary sensors of potentially infectious pathogens. PRRs induce the closure of stomata via activation of guard cell-expressed SLAC-type anion channels to elevate innate immune surveillance of leaf surfaces. Using super-resolution microscopy, FRET applications and split-luciferase assays in combination with electrophysiology, project B08 intends to quantify and to decipher the plasticity and protein-protein interaction dynamics of chitin receptor-mediated initiation of stomatal closure with high spatio/temporal resolution.

• DFG Programme: CRC/Transregios
• Subproject of: TRR 166: High-end light microscopy elucidates membrane receptor function - ReceptorLight
• Applicant Institution: Friedrich-Schiller-Universität Jena
• Project Heads: Professor Dr. Dietmar Geiger; Professor Dr. Rainer Hedrich