Project Details
Projekt
Dissecting the cross talks between tissue resident memory T cells and kidney tissue (A04)
Subject Area
Immunology
Term
since 2016
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 264599542
Aims of the project are: i) identification of TRM cell subsets and mechanisms responsible for the heterologous protection and aggravation of crescentic GN; ii) characterization of TRM cell-induced functional changes of renal hematopoietic and parenchymal cells; iii) uncovering cell–cell interaction between TRM cells, myeloid cells and renal cells; iv) evaluation of the identified T cell - renal cell interactions in human biopsies. In summary, we will determine the consequences of TRM cell – kidney cell interaction for renal immunity and autoimmunity.
DFG Programme
Collaborative Research Centres
Subproject of
SFB 1192:
Immune-Mediated Glomerular Diseases - Basic Concepts and Clinical Implications -
Applicant Institution
Universität Hamburg
