Dihydrogen-mediated sustainable bond forming reactions

• Applicant: Professor Dr. Johannes F. Teichert
• Subject Area: Organic Molecular Chemistry - Synthesis and Characterisation
• Term: since 2017
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 352364740

The development of sustainable reactions is one of the key challenges of the contemporary synthetic chemistry. Sustainable reactions bear the key advantage that they can provide compounds of interest to society (such as agrochemicals or pharmaceuticals) with little or ideally no harmful impact on the environment.The goal of this research program is to develop dihydrogen-mediated reductive coupling reactions with easily accessible catalysts employing first row transition metals (with a special emphasis on copper and nickel). By using dihydrogen (H2) versatile building blocks for organic chemistry can be provided with minimal waste generation. In this manner, a key contribution to the development of sustainable synthetic methods should be made.Key tool to realize the H2 activation will be metal complexes bearing a metal-heteroatom bond, which should facilitate a heterolytic H-H-bond cleavage. In this manner, a proton and a hydride are produced by the H2 activation, which should be used in a variety of follow-up reactions to generate C-C, C-H and C-heteroatom bonds.

• DFG Programme: Independent Junior Research Groups
• Major Instrumentation: Parallelscreeninggerät für Hochdruckreaktionen
• Instrumentation Group: 8620 Strahlungsthermometer, Pyrometer, Thermosonden