Functional role and dynamic change of extinction network connectivity (A03)

• Subject Area: Biological Psychology and Cognitive Neuroscience ; General, Cognitive and Mathematical Psychology ; Human Cognitive and Systems Neuroscience
• Term: since 2017
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 316803389

Using advanced multimodal imaging methods in humans we will test how dynamic interactions between core regions of the extinction network and other related networks shape learning. We will use high-resolution laminar 7T recordings in order to disentangle feedforward and feedback interactions. These experiments will be conducted via simultaneous EEG and 7T fMRI recordings in order to unravel the electrophysiological origins of the aforementioned interactions. We will relate EEG oscillations at different frequencies to layer-resolved fMRI network activity and connectivity. Finally, interindividual differences in learning outcome will be related to variations of pre-learning measures of brain microstructure and functional network connectivity at an unprecedented spatial resolution.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1280: Extinction Learning
• Applicant Institution: Ruhr-Universität Bochum
• Project Heads: Professor Dr. Nikolai Axmacher; Professor Dr. Erhan Genc