Long-term dynamics of the post-synapse in relation to its surroundings (C03)

• Subject Area: Experimental and Theoretical Network Neuroscience ; Bioinformatics and Theoretical Biology
• Term: since 2017
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 317475864

We aim to investigate synaptic memory on a long timescale, by including spine-external processes – that is the spine’s surrounding elements, which could hinder, enhance or bias the actin-induced shape fluctuations either by occupying space or by anchoring the membrane through cell adhesion molecules. In particular, we will focus on the links between dendritic spines and the (A) presynaptic structures, (B) the extracellular matrix (ECM), and/or (C) other cells such as glia.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1286: Quantitative Synaptology
• Applicant Institution: Georg-August-Universität Göttingen
• Project Head: Dr. Michael Fauth