Nanoscale monitoring of surface effects, structural changes, and encapsulation in block copolymer nanostructures using tip-enhanced Raman spectroscopy (B04)

• Subject Area: Polymer Materials
• Term: since 2017
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 316213987

The goal is to gain a fundamental understanding of drug encapsulation and release of polymer-based nanoparticles. Accordingly, nanoscale mechanical (e.g., AFM) and optical (TERS) techniques are adapted to study the associated structure-property relationships with nanometer resolution. For studies related to localisation and release of drugs, model block copolymer micelles will be prepared to study the respective processes at the molecular level.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1278: Polymer-based nanoparticle libraries for targeted anti-inflammatory strategies
• Major Instrumentation: Setup for Dynamic and Static Light Scattering (DLS/SLS)
• Applicant Institution: Friedrich-Schiller-Universität Jena
• Project Heads: Professor Dr. Volker Deckert; Professor Dr. Felix H. Schacher