An inverse approach to the identification and manipulation of neuronal circuits underlying olfactory-mediated habituation/discrimination (B06)

• Subject Area: Molecular Biology and Physiology of Neurons and Glial Cells
• Term: since 2017
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 227953431

This project will examine a central capability of the olfactory system, olfactory habituation. This denotes the capacity to gradually decrease the response to an innate, non-reinforced odor stimulus after a repeated presentation of that stimulus. The project will use in-vivo imaging, as well as inverse approaches using closed loop Cal-Light/FLARE labeling to pinpoint the network and cellular features of the horizontal diagonal band (HDB)-olfactory bulb system relevant for odor habituation and discrimination behavior.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1089: Synaptic Micronetworks in Health and Disease
• Applicant Institution: Rheinische Friedrich-Wilhelms-Universität Bonn
• Project Heads: Professor Dr. Martin Fuhrmann; Karl Martin Schwarz, Ph.D.